1-(Phenylsulfonyl)-3-indolecarboxaldehyde
1-(Phenylsulfonyl)-3-indolecarboxaldehyde (CAS: 80360-20-9; Formula: C15H11NO3S; Molar Mass: 285.32 g/mol) is a sophisticated organic compound featuring an indole core functionalized with a sulfonyl and an aldehyde group. Supplied by Tech Serve Solutions with a 97% assay, this chemical serves as a key intermediate and building block in complex organic synthesis. Its applications span the development of various bioactive molecules, including potential pharmaceuticals.
- IUPAC
- 1-(Benzenesulfonyl)indole-3-carboxaldehyde,1-(Phenylsulfonyl)-3-formylindole,NSC 628191
- Synonyms
- 1-(Benzenesulfonyl)indole-3-carboxaldehyde1-(Phenylsulfonyl)-3-formylindoleNSC 628191
Synthesis of Bioactive Compounds
This compound is a versatile precursor for the synthesis of diverse biologically active molecules. It has been utilized in the preparation of potential antifungal agents, anti-inflammatory drugs, and antitumor compounds, highlighting its significance in medicinal chemistry research.
Intermediate in Organic Synthesis
As a functionalised indole, it acts as a valuable building block for constructing more complex molecular architectures. Its aldehyde group readily participates in various reactions, including Peterson olefination, making it useful for creating new carbon-carbon bonds.
Development of Enzyme Inhibitors
The compound has been investigated as a precursor for molecules with inhibitory activity against key biological enzymes. Research includes its use in developing potential topoisomerase II inhibitors and inhibitors of uracil DNA glycosylase (UNG2).
| Molecular weight | 285.32 |
|---|---|
| Empirical formula | C15H11NO3S |
| Assay | 97% |
| Application | Reactant for:• Peterson olefination1Reactant for preparation of:• Antifungal agents2• Potential topoisomerase II inhibitors3• Anti-inflammatory, analgesic and anticonvulsant agents4• Bacteriorhodopsin analogs5• Antitumor agents6• Antitubercular agents7• Inhibitors of human dUTPase and UNG28• Uracil DNA glycosylase inhibitor9• Anti-HIV and anti-tumor β-carbolines10 |
| Melting point | 157-161 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Phenylsulfonyl)-3-indolecarboxaldehyde used for?
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1-(Phenylsulfonyl)-3-indolecarboxaldehyde is primarily used as a building block and intermediate in organic synthesis, particularly for the preparation of various bioactive compounds, including potential pharmaceutical agents such as antifungal, anti-inflammatory, and antitumor compounds, as well as enzyme inhibitors.
What are the CAS number and chemical formula of this product?
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The CAS number is 80360-20-9 and the chemical formula is C15H11NO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(Phenylsulfonyl)-3-indolecarboxaldehyde with an assay of 97%. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
How should 1-(Phenylsulfonyl)-3-indolecarboxaldehyde be handled safely?
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1-(Phenylsulfonyl)-3-indolecarboxaldehyde is classified as harmful if swallowed (H302). When handling, it is recommended to wear a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, including 1-(Phenylsulfonyl)-3-indolecarboxaldehyde.
How can I request a sample or quote?
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To request a sample or a quotation for 1-(Phenylsulfonyl)-3-indolecarboxaldehyde, please contact the Tech Serve Solutions sales team through our website or by phone.
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