1-(Phenylsulfonyl)indole
1-(Phenylsulfonyl)indole (CAS 40899-71-6), with the molecular formula C14H11NO2S and a molecular weight of 257.31 g/mol, is a key heterocyclic building block. This compound serves as a valuable reactant in the synthesis of diverse biologically active molecules, finding applications in the development of novel therapeutic agents. It is supplied by Tech Serve Solutions with an assay of 98% for research and chemical synthesis purposes.
- IUPAC
- 1-(Benzenesulfonyl)indole,Benzenesulfonic acid indolide,NSC 237040,NSC 683530
- Synonyms
- 1-(Benzenesulfonyl)indoleBenzenesulfonic acid indolideNSC 237040NSC 683530

Preparation of Antiplasmodial Agents
1-(Phenylsulfonyl)indole is utilized as a reactant in the synthesis of compounds with potential antiplasmodial activity, contributing to the search for new antimalarial therapies.
Synthesis of Antifungal Agents
This indole derivative serves as a precursor for the preparation of novel antifungal agents, aiding in the development of treatments against fungal infections.
Development of Anti-HIV-1 Agents
The compound is employed in synthetic routes aimed at producing agents with potential activity against the Human Immunodeficiency Virus type 1 (HIV-1).
Agonists of Histamine H4 Receptor
1-(Phenylsulfonyl)indole is used in the preparation of molecules designed to act as agonists for the histamine H4 receptor, relevant for inflammatory and immune system research.
Synthesis of Antibacterial Agents
Researchers utilise this building block in synthetic pathways targeting the development of new antibacterial compounds to combat bacterial infections.
Preparation of Camalexin Analogs
It acts as a reactant in the synthesis of analogs of Camalexin, a natural product with diverse biological activities, for further investigation.
| Molecular weight | 257.31 |
|---|---|
| Empirical formula | C14H11NO2S |
| Assay | 98% |
| Application | Reactant for preparation of:• Antiplasmodial agents1• Antifungal agents2• Anti HIV-1 agents3• Agonists of the histamine H4 receptor4• Antibacterial agents5• Camalexin analogs6• CDK inhibitors and cytotoxic agents7• Histone Deacetylase inhibitors8 |
| Melting point | 78-80 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Phenylsulfonyl)indole used for?
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1-(Phenylsulfonyl)indole is primarily used as a reactant for the preparation of various biologically active compounds, including antiplasmodial, antifungal, anti-HIV-1, and antibacterial agents, as well as agonists of the histamine H4 receptor and Camalexin analogs.
What is the CAS number and formula for 1-(Phenylsulfonyl)indole?
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The CAS number for 1-(Phenylsulfonyl)indole is 40899-71-6, and its molecular formula is C14H11NO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(Phenylsulfonyl)indole with an assay of 98%. This product is intended for research and chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
How should 1-(Phenylsulfonyl)indole be handled safely?
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1-(Phenylsulfonyl)indole has a WGK Germany classification of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area to avoid exposure.
Is 1-(Phenylsulfonyl)indole available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1-(Phenylsulfonyl)indole, and can fulfil international orders.
How can I request a quote or sample?
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To request a quote or sample of 1-(Phenylsulfonyl)indole, please contact our sales team via the website or direct inquiry.
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