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1-(Phenylsulfonyl)indole

CAS 40899-71-6C14H11NO2SChemical Synthesis

1-(Phenylsulfonyl)indole (CAS 40899-71-6), with the molecular formula C14H11NO2S and a molecular weight of 257.31 g/mol, is a key heterocyclic building block. This compound serves as a valuable reactant in the synthesis of diverse biologically active molecules, finding applications in the development of novel therapeutic agents. It is supplied by Tech Serve Solutions with an assay of 98% for research and chemical synthesis purposes.

IUPAC
1-(Benzenesulfonyl)indole,Benzenesulfonic acid indolide,NSC 237040,NSC 683530
Synonyms
1-(Benzenesulfonyl)indoleBenzenesulfonic acid indolideNSC 237040NSC 683530
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1-(Phenylsulfonyl)indole (C14H11NO2S) — chemical structure, CAS 40899-71-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC13 to C27Chemical SynthesisHeterocyclic Building BlocksIndoles
01 /Applications

Preparation of Antiplasmodial Agents

1-(Phenylsulfonyl)indole is utilized as a reactant in the synthesis of compounds with potential antiplasmodial activity, contributing to the search for new antimalarial therapies.

Synthesis of Antifungal Agents

This indole derivative serves as a precursor for the preparation of novel antifungal agents, aiding in the development of treatments against fungal infections.

Development of Anti-HIV-1 Agents

The compound is employed in synthetic routes aimed at producing agents with potential activity against the Human Immunodeficiency Virus type 1 (HIV-1).

Agonists of Histamine H4 Receptor

1-(Phenylsulfonyl)indole is used in the preparation of molecules designed to act as agonists for the histamine H4 receptor, relevant for inflammatory and immune system research.

Synthesis of Antibacterial Agents

Researchers utilise this building block in synthetic pathways targeting the development of new antibacterial compounds to combat bacterial infections.

Preparation of Camalexin Analogs

It acts as a reactant in the synthesis of analogs of Camalexin, a natural product with diverse biological activities, for further investigation.

02 /Properties
Molecular weight257.31
Empirical formulaC14H11NO2S
Assay98%
ApplicationReactant for preparation of:• Antiplasmodial agents1• Antifungal agents2• Anti HIV-1 agents3• Agonists of the histamine H4 receptor4• Antibacterial agents5• Camalexin analogs6• CDK inhibitors and cytotoxic agents7• Histone Deacetylase inhibitors8
Melting point78-80 °C(lit.)
03 /Identifiers & registry
CAS number
40899-71-6
MDL number
MFCD00134318
PubChem substance
24862680
04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 1-(Phenylsulfonyl)indole used for?

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1-(Phenylsulfonyl)indole is primarily used as a reactant for the preparation of various biologically active compounds, including antiplasmodial, antifungal, anti-HIV-1, and antibacterial agents, as well as agonists of the histamine H4 receptor and Camalexin analogs.

What is the CAS number and formula for 1-(Phenylsulfonyl)indole?

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The CAS number for 1-(Phenylsulfonyl)indole is 40899-71-6, and its molecular formula is C14H11NO2S.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 1-(Phenylsulfonyl)indole with an assay of 98%. This product is intended for research and chemical synthesis; TSS does not represent it as USP, BP, or EP grade.

How should 1-(Phenylsulfonyl)indole be handled safely?

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1-(Phenylsulfonyl)indole has a WGK Germany classification of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area to avoid exposure.

Is 1-(Phenylsulfonyl)indole available for export?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1-(Phenylsulfonyl)indole, and can fulfil international orders.

How can I request a quote or sample?

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To request a quote or sample of 1-(Phenylsulfonyl)indole, please contact our sales team via the website or direct inquiry.

Need 1-(Phenylsulfonyl)indole in a specific grade or volume?