Allopurinol riboside
Allopurinol riboside (CAS: 16220-07-8; Formula: C10H12N4O5; MW: 268.23 g/mol) is a purine analogue with significant biochemical research applications. It functions as an experimental agent investigated for treating parasitic diseases like leishmaniasis and American trypanosomiasis. Allopurinol riboside acts as a potent inhibitor of orotidine 5′-monophosphate decarboxylase in Plasmodium falciparum, highlighting its utility in antiparasitic drug discovery.
- IUPAC
- 1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4-one
Antiparasitic Research Agent
Allopurinol riboside is utilised in research settings as an experimental therapeutic agent. It has been studied for its potential efficacy in treating protozoan infections such as leishmaniasis and American trypanosomiasis.
Enzyme Inhibition Studies
This compound serves as a valuable tool for biochemical research, specifically as an inhibitor of orotidine 5′-monophosphate (OMP) decarboxylase from Plasmodium falciparum (PfODCase). This inhibitory activity is crucial for understanding parasitic metabolic pathways.
Nucleoside Analogue Research
As a nucleoside analogue, Allopurinol riboside is employed in studies investigating the mechanisms of nucleotide metabolism and the development of novel therapeutic compounds targeting related pathways.
| Molecular weight | 268.23 |
|---|---|
| Empirical formula | C10H12N4O5 |
| Storage temperature | 2-8°C |
| Application | Allopurinol riboside is an experimental agent for the treatment of leishmaniasis and American trypanosomiasis. Allopurinol riboside is an inhibitor of orotidine 5′-monophosphate (OMP) decarboxylase from Plasmodium falciparum ((PfODCase, EC 4.1.1.23). |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Allopurinol riboside used for?
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Allopurinol riboside is used as an experimental agent for the treatment of leishmaniasis and American trypanosomiasis, and as an inhibitor of orotidine 5′-monophosphate decarboxylase from Plasmodium falciparum in research settings.
What is the CAS number and formula for Allopurinol riboside?
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The CAS number for Allopurinol riboside is 16220-07-8, and its empirical formula is C10H12N4O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Allopurinol riboside (CAS: 16220-07-8) primarily for research purposes. The specific assay and purity are detailed on the product's Certificate of Analysis, which can be requested. Tech Serve Solutions does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product specifications.
What are the safety and handling recommendations for Allopurinol riboside?
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Handling Allopurinol riboside requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet (SDS) for comprehensive hazard information and handling procedures. The WGK Germany classification is 3.
How is Allopurinol riboside packed, shipped, and exported?
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Allopurinol riboside is typically stored at 2-8°C. Tech Serve Solutions adheres to strict international shipping regulations for the export of fine chemicals, ensuring secure and compliant packaging and transportation.
How can I request a sample or quote for Allopurinol riboside?
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To request a sample or a quote for Allopurinol riboside, please contact the Tech Serve Solutions sales team through the website or by direct inquiry, providing your contact details and intended research application.
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