(R)-(+)-2-Methyl-CBS-oxazaborolidine

CAS 112022-83-0C18H20BNOChemical Synthesis

(R)-(+)-2-Methyl-CBS-oxazaborolidine (CAS: 112022-83-0) is an organoboron compound with the formula C18H20BNO and a molecular weight of 277.17 g/mol. It is a chiral catalyst widely employed in asymmetric synthesis, particularly for the stereoselective reduction of ketones and imines. Its effectiveness in controlling enantioselectivity makes it a valuable reagent in the synthesis of chiral molecules.

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(R)-(+)-2-Methyl-CBS-oxazaborolidine (C18H20BNO) — chemical structure, CAS 112022-83-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsReduction

01 /Applications

Asymmetric Reduction

This oxazaborolidine catalyst is crucial for the enantioselective reduction of prochiral ketones and imines, enabling the synthesis of chiral alcohols and amines with high stereochemical control.

Chiral Synthesis

It serves as a key reagent in asymmetric synthesis, facilitating the construction of enantiomerically enriched compounds vital for pharmaceuticals and fine chemicals.

Catalysis in Organic Chemistry

As a chiral catalyst, it mediates a variety of organic transformations where precise stereochemical outcomes are required, contributing to the development of complex molecular architectures.

02 /Properties

Molecular weight	277.17
Empirical formula	C18H20BNO
Assay	≥95%
Density	0.942 g/mL at 25 °C
Refractive index	n20/D 1.4602
Concentration	1 M in THF
Optical activity	[α]22/D +76.8°, c = 1 in toluene
Melting point	85-95 °C(lit.)
Storage temperature	2-8°C

03 /Safety & handling

Precautionary statements

P210Keep away from heat, sparks and open flames. No smoking
P261Avoid breathing dust, fume, gas or vapours
P281Use personal protective equipment as required
P305IF IN EYES

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

112022-83-0

MDL number

MFCD00078440

PubChem substance

24883644

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(+)-2-Methyl-CBS-oxazaborolidine used for?

(R)-(+)-2-Methyl-CBS-oxazaborolidine is primarily used as a chiral catalyst in asymmetric synthesis for the stereoselective reduction of ketones and imines.

What are the CAS number and formula for (R)-(+)-2-Methyl-CBS-oxazaborolidine?

The CAS number is 112022-83-0, and the empirical formula is C18H20BNO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (R)-(+)-2-Methyl-CBS-oxazaborolidine with an assay of ≥95%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.

How should (R)-(+)-2-Methyl-CBS-oxazaborolidine be handled?

Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Avoid contact with eyes and skin. Store at 2-8°C.

How is this chemical shipped and exported?

Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, capable of shipping and exporting (R)-(+)-2-Methyl-CBS-oxazaborolidine worldwide.