(R)-(+)-2-Methylsuccinic acid 4-methyl ester
(R)-(+)-2-Methylsuccinic acid 4-methyl ester (CAS 81025-83-4), with the linear formula CH₃OCOCH₂CH(CH₃)CO₂H and a molecular weight of 146.14 g/mol, is a valuable chiral building block. This ester is primarily utilised in asymmetric synthesis and general chemical synthesis. Its optical activity, with a specific rotation of +11° (c=1 in chloroform), highlights its importance in stereoselective reactions, making it a key intermediate for creating complex organic molecules.
Chiral Building Block in Asymmetric Synthesis
This enantiomerically pure ester serves as a crucial synthon for introducing chirality into target molecules. Its defined stereochemistry is essential for the stereoselective construction of complex organic compounds, particularly in pharmaceutical research and development.
Intermediate in Organic Synthesis
As a functionalised dicarboxylic acid derivative, it can participate in a variety of organic transformations. It is useful for creating more complex molecular architectures in academic research and industrial chemical synthesis.
Research and Development
Used in laboratories for exploring novel synthetic routes and developing new chemical entities. Its chiral nature makes it a target for various modification reactions to access diverse stereoisomers.
| Molecular weight | 146.14 |
|---|---|
| Linear formula | CH3OCOCH2CH(CH3)CO2H |
| Assay | 95% |
| Boiling point | 241-242 °C/760 mmHg(lit.) |
| Density | 1.150 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4320(lit.) |
| Optical activity | [α]20/D +11°, c = 1 in chloroform |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 38 °C / 100.4 °F |
| Transport (UN / ADR) | UN 3272 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-2-Methylsuccinic acid 4-methyl ester used for?
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(R)-(+)-2-Methylsuccinic acid 4-methyl ester is primarily used as a chiral building block in asymmetric synthesis and general organic chemical synthesis.
What is the CAS number and formula for this chemical?
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The CAS number is 81025-83-4 and the linear formula is CH₃OCOCH₂CH(CH₃)CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-2-Methylsuccinic acid 4-methyl ester with an assay of 95%. This product is supplied for research and chemical synthesis purposes. TSS does not represent it as USP, BP, EP or other pharmacopoeia grade.
How should this chemical be handled safely?
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This compound is flammable (flash point 38 °C) and may cause skin, eye, and respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Consult the Safety Data Sheet for full details.
Is this product a controlled substance?
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The provided data does not indicate that (R)-(+)-2-Methylsuccinic acid 4-methyl ester is a controlled substance.
How is this product packed and shipped?
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(R)-(+)-2-Methylsuccinic acid 4-methyl ester is shipped according to UN 3272 standards for flammable liquids. TSS is a global supplier and exporter, adhering to all international shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of (R)-(+)-2-Methylsuccinic acid 4-methyl ester, please contact the TSS sales department through our website or by phone.
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