Trimethyl orthoacetate
Trimethyl orthoacetate (CAS: 1445-45-0), with the molecular formula CH3C(OCH3)3 and a molecular weight of 120.15 g/mol, is a versatile organic compound. It functions as a building block in chemical synthesis, particularly in the preparation of complex purine derivatives. This orthoester is supplied by Tech Serve Solutions for research and development purposes, offering reliable quality for various synthetic pathways.
- IUPAC
- 1,1,1-Trimethoxyethane
Synthesis of Purine Derivatives
Trimethyl orthoacetate is employed in the preparation of specific purine compounds, such as 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and related structures. Its role is crucial in establishing the required molecular architecture for these complex molecules.
Organic Building Block
As an ortho ester, this compound serves as a valuable building block in organic synthesis. It facilitates reactions requiring the introduction of specific functional groups or skeletal modifications in target molecules.
Chemical Synthesis Reagent
This chemical is utilised in various chemical synthesis processes where its reactive properties can be leveraged. It is suitable for laboratory-scale research and development activities.
| Molecular weight | 120.15 |
|---|---|
| Linear formula | CH3C(OCH3)3 |
| Assay | 99% |
| Boiling point | 107-109 °C(lit.) |
| Density | 0.944 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.388(lit.) |
| Application | Trimethyl orthoacetate has been used in the preparation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyl-oxymethyl-4-alkoxycarbonyloxybut -1-yl)purines1. |
Hazard statements
- H225Highly flammable liquid and vapour
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 15 °C / 59 °F |
| Transport (UN / ADR) | UN 3272 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
| Safety statements (S) | 16 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethyl orthoacetate used for?
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Trimethyl orthoacetate is primarily used as a building block in organic synthesis, notably in the preparation of specific purine derivatives. It is also utilised in general chemical synthesis.
What are the CAS number and molecular formula for Trimethyl orthoacetate?
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The CAS number for Trimethyl orthoacetate is 1445-45-0, and its molecular formula is CH3C(OCH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethyl orthoacetate with an assay of 99%. This is a technical or research grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Trimethyl orthoacetate be handled safely?
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Trimethyl orthoacetate is a highly flammable liquid and vapour (H225). Handle with extreme caution, keeping away from heat, sparks, open flames, and hot surfaces. Use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Store in a well-ventilated place.
How is Trimethyl orthoacetate shipped and exported?
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Trimethyl orthoacetate is shipped and exported according to international regulations for hazardous materials, identified under UN 3272, Hazard Class 3, Packing Group II.
How can I request a sample or quote for Trimethyl orthoacetate?
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To request a sample or a quote for Trimethyl orthoacetate, please contact the Tech Serve Solutions sales team through the website or by phone.
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