Phenethylmagnesium chloride solution
Phenethylmagnesium chloride solution (CAS: 90878-19-6), with the linear formula C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>CH<sub>2</sub>MgCl and a molecular weight of 164.92, is a Grignard reagent supplied at 1.0 M in THF. This organometallic compound is a valuable synthetic intermediate, primarily employed in organic synthesis for introducing the phenethyl group into various molecules. Its reactivity makes it suitable for carbon-carbon bond formation in complex chemical constructions.
Organic Synthesis Reagent
Phenethylmagnesium chloride solution serves as a nucleophilic source of the phenethyl group in organic synthesis. It is extensively used for the formation of new carbon-carbon bonds through reactions with electrophiles like aldehydes, ketones, esters, and epoxides.
Pharmaceutical Intermediate Production
This Grignard reagent is applicable in the multi-step synthesis of pharmaceutical compounds. It enables the efficient introduction of the phenethyl moiety, a structural feature found in various active pharmaceutical ingredients (APIs).
Fine Chemical Manufacturing
The compound is utilised in the manufacture of fine chemicals where precise control over alkylation is required. It facilitates the synthesis of complex organic molecules for diverse industrial applications beyond pharmaceuticals.
| Molecular weight | 164.92 |
|---|---|
| Linear formula | C6H5CH2CH2MgCl |
| Boiling point | 65 °C |
| Density | 0.954 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14/15-19-20/21/22-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenethylmagnesium chloride solution used for?
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Phenethylmagnesium chloride solution is primarily used as a reagent in organic synthesis for introducing the phenethyl group into other molecules, facilitating carbon-carbon bond formation in the production of pharmaceuticals and fine chemicals.
What is the CAS number and formula for Phenethylmagnesium chloride solution?
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The CAS number for Phenethylmagnesium chloride solution is 90878-19-6, and its linear formula is C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>CH<sub>2</sub>MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenethylmagnesium chloride solution at a concentration of 1.0 M in THF. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should Phenethylmagnesium chloride solution be handled safely?
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Phenethylmagnesium chloride solution is a Danger-level hazardous material, flammable, corrosive, and potentially causes respiratory irritation and cancer. It reacts violently with water and may form explosive peroxides. Handle with extreme care, using appropriate personal protective equipment including face shields, gloves, goggles, and suitable respirators. Ensure adequate ventilation and avoid contact with water or moisture.
How is Phenethylmagnesium chloride solution packed and shipped?
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Phenethylmagnesium chloride solution is packed and shipped according to strict international regulations for hazardous materials, including UN 2924 classification. We ensure secure packaging and compliant export documentation for global distribution.
How can I request a sample or quote for Phenethylmagnesium chloride solution?
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To request a sample or a quote for Phenethylmagnesium chloride solution, please contact our sales department directly through our website or by phone, providing your specific requirements and delivery details.
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