1-Boc-4-(2-hydroxyethyl)piperazine
1-Boc-4-(2-hydroxyethyl)piperazine (CAS: 77279-24-4, C11H22N2O3) is a valuable heterocyclic building block with a molecular weight of 230.30 g/mol. It features a piperazine ring protected with a Boc group and functionalised with a hydroxyethyl substituent. This compound serves as a key intermediate in organic synthesis, particularly for the construction of more complex molecules in pharmaceutical and chemical research.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), where the piperazine moiety is a common structural motif. Its functional groups allow for diverse synthetic transformations.
Chemical Synthesis
Serves as a versatile building block in general organic synthesis for creating novel chemical entities. The Boc protection and hydroxyethyl group offer distinct reaction pathways.
Heterocyclic Chemistry
A useful reagent for the preparation of various nitrogen-containing heterocyclic compounds. Its structure lends itself to derivatisation and incorporation into larger molecular frameworks.
| Molecular weight | 230.30 |
|---|---|
| Empirical formula | C11H22N2O3 |
| Assay | 97% |
| Melting point | 38-42 °C |


Hazard statements
- H301Toxic if swallowed
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-50 |
| Safety statements (S) | 45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-4-(2-hydroxyethyl)piperazine used for?
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1-Boc-4-(2-hydroxyethyl)piperazine is primarily used as a building block in organic synthesis, especially for the preparation of complex molecules in pharmaceutical research and chemical development.
What is the CAS number and chemical formula for 1-Boc-4-(2-hydroxyethyl)piperazine?
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The CAS number is 77279-24-4 and the chemical formula is C11H22N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Boc-4-(2-hydroxyethyl)piperazine with an assay of 97%. We do not represent this product as USP, BP, EP, or for nutraceutical, food, or medicinal use.
What are the main safety hazards associated with 1-Boc-4-(2-hydroxyethyl)piperazine?
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This compound is classified as toxic if swallowed (H301) and very toxic to aquatic life (H400), with a Danger signal word. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirators, should be used during handling. It is also an environmental hazard.
How is 1-Boc-4-(2-hydroxyethyl)piperazine packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging details will be provided upon request, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for 1-Boc-4-(2-hydroxyethyl)piperazine?
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Please contact our sales team directly via phone or email to request a sample or a quotation for 1-Boc-4-(2-hydroxyethyl)piperazine.
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