1-Boc-4-(3-hydroxypropyl)piperazine
1-Boc-4-(3-hydroxypropyl)piperazine (CAS: 132710-90-8, C12H24N2O3) is a versatile heterocyclic building block with a molecular weight of 244.33 g/mol. This compound, also known as tert-Butyl-4-(3-hydroxypropyl)piperazine-1-carboxylate, serves as a valuable intermediate in organic synthesis. Its structure, featuring a Boc-protected piperazine ring and a hydroxypropyl chain, allows for diverse chemical modifications and incorporation into complex molecular architectures.
- IUPAC
- tert-Butyl-4-(3-hydroxypropyl)piperazine-1-carboxylate

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programmes. Its functional groups enable further elaboration into potential therapeutic agents.
Chemical Synthesis
A key building block for constructing complex organic molecules. The piperazine core and reactive hydroxyl group offer numerous possibilities for derivatisation.
Research Reagent
Employed in academic and industrial research laboratories for exploring novel chemical reactions and developing new compounds.
| Molecular weight | 244.33 |
|---|---|
| Empirical formula | C12H24N2O3 |
| Assay | 97% |
| Melting point | 73-77 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-4-(3-hydroxypropyl)piperazine used for?
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1-Boc-4-(3-hydroxypropyl)piperazine is primarily used as a building block in chemical synthesis and as an intermediate in the development of pharmaceuticals and other complex organic molecules.
What is the CAS number and chemical formula for 1-Boc-4-(3-hydroxypropyl)piperazine?
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The CAS number is 132710-90-8 and the empirical formula is C12H24N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Boc-4-(3-hydroxypropyl)piperazine with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Boc-4-(3-hydroxypropyl)piperazine be handled?
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This compound is dangerous if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation (H301, H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator. Ensure adequate ventilation.
Is 1-Boc-4-(3-hydroxypropyl)piperazine a controlled substance?
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Based on the provided data, there is no indication that 1-Boc-4-(3-hydroxypropyl)piperazine is a controlled substance.
How is 1-Boc-4-(3-hydroxypropyl)piperazine packed and shipped?
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1-Boc-4-(3-hydroxypropyl)piperazine is shipped as UN 2811, Class 6.1, Packing Group III. Tech Serve Solutions is a global supplier and exporter, adhering to all relevant shipping regulations.
How can I request a sample or quote for 1-Boc-4-(3-hydroxypropyl)piperazine?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for 1-Boc-4-(3-hydroxypropyl)piperazine.
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