1-Boc-4-(4-formylphenyl)piperazine
1-Boc-4-(4-formylphenyl)piperazine (CAS: 197638-83-8) is a complex organic molecule with the formula C16H22N2O3 and a molecular weight of 290.36 g/mol. This piperazine derivative functions as a valuable building block in organic synthesis, particularly in the development of pharmaceutical intermediates and advanced materials. Its structure incorporates both a protected amine and an aldehyde functional group, enabling diverse chemical transformations for creating novel compounds.
- IUPAC
- 4-(N-Boc-piperazin-1-yl)benzaldehyde,tert-Butyl 4-(4′-formylphenyl)piperazine-1-carboxylate
- Synonyms
- tert-Butyl 4-(4′-formylphenyl)piperazine-1-carboxylate

Pharmaceutical Intermediate Synthesis
This compound serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). The protected piperazine ring and the reactive aldehyde group allow for the introduction of complex molecular architectures relevant to drug discovery.
Organic Building Block
As a versatile organic building block, it is utilised in research and development for creating novel chemical entities. Its dual functionality facilitates diverse reaction pathways in multi-step synthetic processes.
Material Science Research
The unique structure of 1-Boc-4-(4-formylphenyl)piperazine makes it a candidate for incorporation into advanced materials, potentially influencing their electronic or structural properties.
| Molecular weight | 290.36 |
|---|---|
| Empirical formula | C16H22N2O3 |
| Assay | 97% |
| Melting point | 118-121 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-43 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-4-(4-formylphenyl)piperazine used for?
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1-Boc-4-(4-formylphenyl)piperazine is primarily used as a building block in organic synthesis, particularly for creating pharmaceutical intermediates and in material science research.
What is the CAS number and formula for 1-Boc-4-(4-formylphenyl)piperazine?
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The CAS number is 197638-83-8 and the molecular formula is C16H22N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. It is not supplied as USP, BP, EP, or any other pharmacopoeia grade, and TSS does not represent it as such.
How should 1-Boc-4-(4-formylphenyl)piperazine be handled safely?
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Due to its hazardous nature (Danger, H301, H317), handle with extreme caution. Use appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator. Ensure adequate ventilation and follow emergency procedures as outlined by the safety data sheet.
How is 1-Boc-4-(4-formylphenyl)piperazine packed and shipped?
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This chemical is packed and shipped according to UN 2811 6.1 / PGIII regulations. Specific packing and shipping details for export can be confirmed upon order.
How can I request a sample or a quote for 1-Boc-4-(4-formylphenyl)piperazine?
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Samples and quotes can be requested by contacting the Tech Serve Solutions sales team through our website or direct contact details.
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