4-Methoxyphenethylamine
4-Methoxyphenethylamine (CAS: 55-81-2), a primary amine with the molecular formula C9H13NO, is a valuable building block in chemical synthesis. Its structure, featuring a methoxy group on a phenethylamine core, allows for diverse derivatization. This compound is instrumental in the development of complex organic molecules, including pharmaceuticals and specialised polymers, as documented in scientific literature. Tech Serve Solutions offers 4-Methoxyphenethylamine for research and synthesis applications.
- IUPAC
- 2-(4-Methoxyphenyl)ethylamine,4-Methoxyphenethylamine

Synthesis of Heterocyclic Compounds
4-Methoxyphenethylamine serves as a key precursor in the synthesis of complex heterocyclic structures, such as pyrrolo[3,2-c]carbazole derivatives. These compounds are of interest in medicinal chemistry and materials science.
Polymer Development
This amine is utilised in the creation of specialised polymers, including poly(4-methoxyphenethyl amine) and organopolyphosphazenes. These polymers find applications in areas requiring the immobilisation of bases and oligonucleotides.
Organic Synthesis Building Block
As a versatile organic building block, 4-Methoxyphenethylamine is employed in various synthetic routes for constructing novel organic molecules. Its reactivity makes it suitable for incorporating the methoxy-substituted phenethyl moiety.
| Molecular weight | 151.21 |
|---|---|
| Linear formula | CH3OC6H4CH2CH2NH2 |
| Assay | ≥98% |
| Boiling point | 138-140 °C/20 mmHg(lit.)254-256 °C |
| Density | 1.031 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.538(lit.) |
| Application | 4-Methoxyphenethylamine was used in the synthesis of :• pyrrolo[3,2-c]carbazole1• poly(4-methoxyphenethylamine), required for the immobilization of nitrogenated bases and oligonucleotides2• organopolyphosphazenes such as poly[bis(4-methoxy benzylamino)polyphosphazene] and poly[bis(4-methoxyphenethylamino)polyphosphazene]3 |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary applications of 4-Methoxyphenethylamine?
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4-Methoxyphenethylamine is used as a building block in organic synthesis, including the preparation of heterocyclic compounds like pyrrolo[3,2-c]carbazole, and in the development of specialised polymers such as poly(4-methoxyphenethyl amine) and organopolyphosphazenes.
What is the CAS number and molecular formula for 4-Methoxyphenethylamine?
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The CAS number for 4-Methoxyphenethylamine is 55-81-2, and its molecular formula is C9H13NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxyphenethylamine with an assay of ≥98%. This is a technical grade suitable for research and chemical synthesis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main safety hazards associated with 4-Methoxyphenethylamine?
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4-Methoxyphenethylamine is classified as corrosive, indicated by the GHS05 symbol and signal word 'Danger'. It carries the hazard statement H314, meaning it causes severe skin burns and eye damage. Appropriate personal protective equipment, including gloves, goggles, and face shields, is essential.
How is 4-Methoxyphenethylamine packaged and exported?
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4-Methoxyphenethylamine is carefully packaged according to regulatory standards for safe handling, storage, and international shipment. As a global supplier and exporter, TSS ensures compliance with all relevant shipping regulations.
How can I request a quote or sample of 4-Methoxyphenethylamine?
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To request a quote or sample, please contact our sales department through the website or by telephone. Provide the product name and CAS number (55-81-2) for prompt service.
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