Tanshinone IIA
Tanshinone IIA (CAS: 568-72-9), with the molecular formula C19H18O3 and a molecular weight of 294.34, is a naturally occurring compound. It is recognised for its vasoactive and cardioprotective properties. Research indicates its utility in studies aimed at understanding mechanisms of action, including inhibiting LDL oxidation, monocyte adhesion, and smooth muscle cell proliferation.
- IUPAC
- 1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione,Dan Shen ketone
- Synonyms
- 1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dioneDan Shen ketone
Cardiovascular Research
Tanshinone IIA is investigated for its potential cardioprotective effects, including inhibiting LDL oxidation and monocyte adhesion to the endothelium. It is also studied for its impact on smooth muscle cell migration and proliferation.
Antitumor Agent Research
As an antitumor agent, Tanshinone IIA is explored for its anti-proliferative properties. Its mechanisms against cancer cells are a subject of ongoing scientific inquiry.
Cell Biology Studies
This compound is employed in cell biology research to understand its effects on cellular processes such as proliferation and inflammatory responses.
Phytochemical Analysis
Tanshinone IIA serves as a reference compound in the analysis of phytochemicals, particularly within the classification of terpenes and terpenoids found in herbal medicine.
| Molecular weight | 294.34 |
|---|---|
| Empirical formula | C19H18O3 |
| Assay | ≥97% (HPLC) |
| Form | powder, red |
| Solubility | methanol: soluble5 mg/mL, clear, red-orange to red |
| Storage temperature | 2-8°C |
| Application | Tanshinone IIA (Dan Shen ketone), vasoactive cardioprotective drug, is used in a wide variety of studies to asses is potential therapeutic value and mechanisms of action which include inhibiting LDL oxidation, monocyte adhesion to endothelium, smooth muscle cell migration and proliferation, macrophage cholesterol accumulation, proinflammatory cytokine expression and platelet aggregation. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tanshinone IIA used for?
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Tanshinone IIA is used in research as a vasoactive cardioprotective drug, and studies investigate its potential to inhibit LDL oxidation, monocyte adhesion, smooth muscle cell migration and proliferation, and inflammatory cytokine expression.
What are the CAS number and formula for Tanshinone IIA?
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The CAS number for Tanshinone IIA is 568-72-9, and its empirical formula is C19H18O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tanshinone IIA with a purity of ≥97% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Tanshinone IIA be handled and stored?
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Handling Tanshinone IIA requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 or P1 respirator filter. It should be stored at 2-8°C.
Is Tanshinone IIA a controlled substance?
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The provided data does not indicate that Tanshinone IIA is a controlled substance. Its German Water Hazard Class (WGK) is 3.
How can I request a quote or sample of Tanshinone IIA?
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To request a quote or sample of Tanshinone IIA, please contact the Tech Serve Solutions sales team through our website or by calling our sales department.
How is Tanshinone IIA packed and shipped?
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Tanshinone IIA is typically supplied as a red powder. Specific packing and shipping details for export will be confirmed upon order placement and are subject to international shipping regulations.
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