4-Methoxyphenethylmagnesium chloride solution
4-Methoxyphenethylmagnesium chloride solution (CAS: 211115-05-8) is an organometallic compound with the linear formula H₃COC₆H₄CH₂CH₂MgCl and a molecular weight of 194.94 g/mol. This Grignard reagent, supplied as a 0.5 M solution in THF, is a key intermediate in organic synthesis. It is widely employed for the introduction of the 4-methoxyphenethyl moiety into various organic molecules, facilitating complex chemical transformations.
Organic Synthesis Intermediate
Utilised as a Grignard reagent to form new carbon-carbon bonds by reacting with electrophiles such as aldehydes, ketones, and esters. This allows for the construction of more complex molecular architectures.
Pharmaceutical Intermediate
Serves as a crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its specific reactivity enables the precise incorporation of the methoxy-substituted phenethyl group.
Agrochemical Synthesis
Contributes to the development of novel agrochemicals by facilitating the formation of specific structural motifs required for biological activity.
| Molecular weight | 194.94 |
|---|---|
| Linear formula | H3COC6H4CH2CH2MgCl |
| Boiling point | 65 °C |
| Density | 0.925 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxyphenethylmagnesium chloride solution used for?
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4-Methoxyphenethylmagnesium chloride solution is primarily used as a Grignard reagent in organic synthesis to introduce the 4-methoxyphenethyl group into target molecules, particularly in the pharmaceutical and agrochemical industries.
What is the CAS number and formula for this chemical?
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The CAS number is 211115-05-8 and the linear formula is H₃COC₆H₄CH₂CH₂MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not specify pharmacopoeia grades (e.g., USP, EP) unless explicitly stated in the product data. For specific purity requirements, please contact our sales team.
How should 4-Methoxyphenethylmagnesium chloride solution be handled safely?
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This is a highly flammable liquid and vapour (H225) and causes serious eye irritation (H319), and may cause respiratory irritation (H335). It is suspected of causing cancer (H351) and may form explosive peroxides. Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment. Store refrigerated at 2-8°C.
How is 4-Methoxyphenethylmagnesium chloride solution packed, shipped, and exported?
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This product is packaged according to its hazard classification (UN 2924, Hazard Class 8(3), Packing Group II) to ensure safe transport. We are experienced global exporters, adhering to all international shipping regulations.
How can I request a sample or a quote?
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To request a sample or a quote for 4-Methoxyphenethylmagnesium chloride solution, please visit the 'Contact Us' section of the Tech Serve Solutions website or email our sales department directly.
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