(Chloromethyl)polystyrene
(Chloromethyl)polystyrene, CAS 55844-94-5, is a crosslinked polymer support. It is supplied on a 2% DVB matrix with a particle size of 200-400 mesh. This versatile resin is primarily utilised as a polymer support in solid-phase synthesis, particularly for Boc-/Bzl-SPPS (Solid-Phase Peptide Synthesis). Its reactive chloromethyl groups allow for efficient anchoring of amino acids and other molecules, facilitating complex organic synthesis.
- IUPAC
- Merrifield resin

Solid-Phase Peptide Synthesis (SPPS)
(Chloromethyl)polystyrene is a key resin for SPPS, commonly known as Merrifield resin. It provides a solid support for the stepwise assembly of peptide chains using Boc or Bzl protecting group strategies.
Organic Synthesis
The reactive chloromethyl functionality enables its use in various organic synthesis applications where a solid-supported reagent or scaffold is required. It can be functionalised further for diverse synthetic pathways.
Chemical Biology Research
As a functionalised polymer, it serves as a platform in chemical biology for the immobilisation of biomolecules or the synthesis of specialised probes and combinatorial libraries.
| Storage temperature | 2-8°C |
|---|---|
| Particle size | 200-400 mesh |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Matrix | crosslinked with 2% DVB |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Chloromethyl)polystyrene used for?
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(Chloromethyl)polystyrene is primarily used as a polymer support for solid-phase peptide synthesis (SPPS), particularly for Boc/Bzl strategies, and in general organic synthesis applications.
What is the CAS number and formula for (Chloromethyl)polystyrene?
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The CAS number for (Chloromethyl)polystyrene is 55844-94-5. The chemical formula is not applicable as it is a polymer.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Chloromethyl)polystyrene as a crosslinked polymer support with 2% DVB and a particle size of 200-400 mesh. It is not supplied as USP, BP, or EP grade.
How should (Chloromethyl)polystyrene be handled and stored?
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Handle (Chloromethyl)polystyrene with care, using eyeshields and gloves. Store the material at 2-8°C. It is classified under WGK 3 in Germany.
How is (Chloromethyl)polystyrene packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports (Chloromethyl)polystyrene globally, adhering to all necessary regulations for chemical transport.
How can I request a sample or quote for (Chloromethyl)polystyrene?
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To request a sample or a quote for (Chloromethyl)polystyrene, please contact our sales team via the website or direct enquiry form.
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