(Chloromethyl)cyclopropane
(Chloromethyl)cyclopropane (CAS 5911-08-0) is an organochlorine compound with the molecular formula C3H5CH2Cl and a molecular weight of 90.55 g/mol. This flammable liquid serves as a valuable building block in organic synthesis. It is primarily utilised in the preparation of organometallic reagents and as an intermediate in the synthesis of more complex molecules within the chemical and pharmaceutical industries.
Synthesis of Organometallic Reagents
(Chloromethyl)cyclopropane is employed in the generation of organolithium compounds, such as (lithiomethyl)cyclopropane and homoallyllithium. This transformation is typically facilitated by lithiation reactions catalysed by specific reagents like 4,4′-di-tert-butylbiphenyl or naphthalene.
Organic Synthesis Intermediate
As a halogenated hydrocarbon, this compound functions as a versatile intermediate in various organic synthesis pathways. Its reactivity allows for the introduction of the cyclopropylmethyl group into target molecules.
Chemical Research and Development
It serves as a reagent in research laboratories for exploring novel synthetic routes and developing new chemical entities across diverse scientific disciplines.
| Molecular weight | 90.55 |
|---|---|
| Linear formula | C3H5CH2Cl |
| Assay | 97% |
| Boiling point | 87-89 °C(lit.) |
| Density | 0.98 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.435(lit.) |
| Application | (Chloromethyl)cyclopropane was used in the synthesis of (lithiomethyl)cyclopropane and homoallyllithium via 4,4′-di-tert-butylbiphenyl or naphthalene-catalysed lithiation reaction1. |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -2 °C / 28.4 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Chloromethyl)cyclopropane used for?
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(Chloromethyl)cyclopropane is used as a building block in organic synthesis, particularly for the preparation of organometallic reagents and as an intermediate in chemical synthesis.
What is the CAS number and formula for (Chloromethyl)cyclopropane?
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The CAS number is 5911-08-0, and the molecular formula is C3H5CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Chloromethyl)cyclopropane with an assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.
How should (Chloromethyl)cyclopropane be handled safely?
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This compound is a flammable liquid and an irritant. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, keeping it away from ignition sources. Refer to the safety data sheet for comprehensive handling guidelines.
Is (Chloromethyl)cyclopropane a controlled substance?
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The provided data does not indicate that (Chloromethyl)cyclopropane is a controlled substance.
How is (Chloromethyl)cyclopropane packed and shipped?
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(Chloromethyl)cyclopropane is shipped as a UN 1993, Flammable liquid, n.o.s. (Chloromethyl)cyclopropane, 3, PG II. Specific packaging details are available upon request, and TSS adheres to all relevant export regulations.
How can I request a quote or sample of (Chloromethyl)cyclopropane?
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To request a quote or a sample of (Chloromethyl)cyclopropane, please contact our sales department via the website or provide your details through the online inquiry form.
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