(Chloromethyl)-isopropoxy-dimethylsilane
(Chloromethyl)-isopropoxy-dimethylsilane (CAS 18171-11-4) is an organosilicon compound with the linear formula ClCH₂Si(CH₃)₂OCH(CH₃)₂ and a molecular weight of 166.72 g/mol. This clear liquid, with a refractive index of n20/D 1.415, serves as a valuable reagent in chemical synthesis. Its properties make it suitable for incorporation into various organic and organometallic reactions, contributing to the development of novel materials and compounds.
- IUPAC
- (Chloromethyl)dimethylisopropoxysilane

Organosilicon Synthesis
Utilised as a building block in the synthesis of complex organosilicon compounds. Its chloromethyl group allows for facile nucleophilic substitution reactions, enabling the introduction of the dimethylisopropoxysilyl moiety into target molecules.
Chemical Intermediates
Serves as a key intermediate in multi-step organic syntheses. It facilitates the formation of carbon-silicon bonds, which are crucial in the development of specialised polymers and functional materials.
Reagent in Organic Chemistry
Employed as a reactive intermediate for introducing specific functional groups in organic molecules. Its siloxane linkage and reactive chloromethyl group offer versatile reactivity pathways for synthetic chemists.
| Molecular weight | 166.72 |
|---|---|
| Linear formula | ClCH2Si(CH3)2OCH(CH3)2 |
| Assay | 97% |
| Boiling point | 64-66 °C/54 mmHg(lit.) |
| Density | 0.926 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.415(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 28 °C / 82.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Chloromethyl)-isopropoxy-dimethylsilane used for?
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This compound is primarily used as a reagent and intermediate in chemical synthesis, particularly in the field of organosilicon chemistry for creating complex molecules and materials.
What is the CAS number and chemical formula for this product?
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The CAS number is 18171-11-4, and the linear formula is ClCH₂Si(CH₃)₂OCH(CH₃)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
What are the primary safety hazards associated with (Chloromethyl)-isopropoxy-dimethylsilane?
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This compound is classified as flammable (H226) and is an irritant to skin (H315), eyes (H319), and the respiratory system (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used when handling.
How is this chemical shipped and exported?
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The product is shipped according to UN 1993C 3 / PGIII regulations, indicating it is a flammable liquid, Class 3, Packing Group III. TSS is experienced in global export and can provide details upon request.
How can I request a sample or quote for (Chloromethyl)-isopropoxy-dimethylsilane?
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To request a sample or a quotation, please contact the TSS sales department via our website or direct email, providing your specific requirements and shipping details.
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