Clofibrate
Clofibrate (CAS: 637-07-0), with the molecular formula C12H15ClO3 and a molecular weight of 242.70 g/mol, is an organic ester compound. It is primarily recognised for its role in biochemical research, particularly in studies related to lipid metabolism and cell biology. Its chemical structure lends itself to applications as a building block in organic synthesis and as a tool for investigating cellular processes.
- IUPAC
- 2-(4-Chlorophenoxy)-2-methylpropionic acid ethyl ester,Ethyl 2-(4-chlorophenoxy)-2-methylpropionate,Ethyl 2-(4-chlorophenoxy)isobutyrate
- Synonyms
- 2-(4-Chlorophenoxy)-2-methylpropionic acid ethyl esterEthyl 2-(4-chlorophenoxy)-2-methylpropionateEthyl 2-(4-chlorophenoxy)isobutyrate
Biochemical Research
Clofibrate is utilised in research settings to investigate mechanisms of lipid metabolism, including the regulation of peroxisome proliferator-activated receptors (PPARs). Its actions on cellular pathways make it a valuable tool for understanding metabolic diseases.
Organic Synthesis
As an ester containing a chlorinated aromatic ring, Clofibrate can serve as an intermediate or building block in the synthesis of more complex organic molecules. Its functional groups allow for various chemical transformations.
Cell Biology Studies
The compound is employed in cell biology to probe cellular responses, drug-induced effects, and the function of specific organelles like peroxisomes. It helps researchers elucidate fundamental biological processes.
| Molecular weight | 242.70 |
|---|---|
| Empirical formula | C12H15ClO3 |
| Assay | ≥98.0% (GC) |
| Boiling point | 154-156 °C/20 mmHg(lit.) |
| Density | 1.137 g/mL at 20 °C |
| Refractive index | n20/D 1.503 |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3082 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-37/38-41-51/53 |
| Safety statements (S) | 26-36/37/39-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Clofibrate used for?
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Clofibrate is used in biochemical research to study lipid metabolism and peroxisome proliferator-activated receptors (PPARs), as well as in cell biology studies and organic synthesis.
What are the CAS number and formula for Clofibrate?
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The CAS number for Clofibrate is 637-07-0 and its empirical formula is C12H15ClO3.
What grade and purity does Tech Serve Solutions supply for Clofibrate?
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Tech Serve Solutions supplies Clofibrate with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should Clofibrate be handled and stored?
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Clofibrate is classified as Danger, with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). It should be stored at 2-8°C and handled with appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection.
Is Clofibrate a controlled substance?
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Based on the provided data, Clofibrate is not indicated as a controlled or scheduled substance.
How are Clofibrate products packed, shipped, and exported?
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Clofibrate is shipped according to regulations, for example, as UN 3082 9 / PGIII. For export, please contact Tech Serve Solutions for specific requirements and documentation.
How can I request a quote or sample of Clofibrate?
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To request a quote or sample of Clofibrate, please contact our sales team through the details provided on the Tech Serve Solutions website.
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