CGS-15943
CGS-15943 (CAS: 104615-18-1), with the empirical formula C13H8ClN5O and a molecular weight of 285.69 g/mol, is a white solid chemical. It functions as an antagonist, particularly related to adenosine and P2 nucleotide receptors. This compound is valuable in research settings for cell signaling and neuroscience studies, contributing to a deeper understanding of cell biology and neurotransmission.
- IUPAC
- 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
Neuroscience Research
CGS-15943 is employed as a research tool in neuroscience to investigate the roles of adenosine and P2 nucleotide receptors in cellular signaling and neurotransmission pathways. Its antagonist properties aid in elucidating receptor function.
Cell Signaling Studies
This compound serves as a biochemical reagent for studying complex cellular communication mechanisms, specifically focusing on the modulation of purinergic receptors. It helps researchers understand signal transduction processes.
Drug Discovery and Development
As a bioactive small molecule and a GPCR modulator, CGS-15943 can be utilised in early-stage drug discovery programmes targeting neurological disorders or conditions influenced by purinergic signalling.
| Molecular weight | 285.69 |
|---|---|
| Empirical formula | C13H8ClN5O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >10 mg/mLH2O: insoluble |
| Storage temperature | room temp |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora1(29290), Adora2a(25369), Adora2b(29316) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CGS-15943 used for?
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CGS-15943 is used as a research chemical, primarily as an antagonist for adenosine and P2 nucleotide receptors, aiding studies in neuroscience, cell signaling, and cell biology.
What are the CAS number and formula for CGS-15943?
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The CAS number for CGS-15943 is 104615-18-1, and its empirical formula is C13H8ClN5O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies CGS-15943 with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmaceutical grade.
How is CGS-15943 handled and stored?
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Handle CGS-15943 with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Store at room temperature. Note that it is insoluble in water but soluble in DMSO (>10 mg/mL).
What are the primary hazards associated with CGS-15943?
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CGS-15943 is classified with WGK Germany 3, indicating a significant hazard.
How can I request a quote or sample for CGS-15943?
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To request a quote or sample of CGS-15943, please contact our sales team through our website or by phone. We are a global supplier and exporter.
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