CHES

CAS 103-47-9C8H17NO3SBiochemicals & Reagents

CHES (CAS: 103-47-9), chemical formula C8H17NO3S and molecular weight 207.29 g/mol, is a high-purity sulfonic acid derivative. It is recognised for its buffering capacity within a specific pH range. This compound finds utility primarily in the field of diagnostic assay manufacturing, where precise pH control is essential for reliable biochemical reactions and analyses. Its reliable performance makes it a valuable reagent in laboratory settings.

IUPAC: 2-(Cyclohexylamino)ethanesulfonic acid
Synonyms: 2-(Cyclohexylamino)ethanesulfonic acid

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CHES (C8H17NO3S) — chemical structure, CAS 103-47-9; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsBiological BuffersBuffers A to ZGood’s Buffers

01 /Applications

Diagnostic Assay Manufacturing

CHES serves as a critical buffer component in the development and production of diagnostic assays. Its stable buffering capacity ensures optimal conditions for enzymatic reactions and immunoassays, contributing to the accuracy and reproducibility of diagnostic tests.

Biochemical Research

In biochemical research, CHES is employed as a biological buffer. Its pKa value allows for stable pH maintenance in experimental systems, supporting studies in enzymology, protein chemistry, and molecular biology where pH sensitivity is a concern.

Laboratory Reagent

As a general laboratory reagent, CHES is supplied for various analytical and preparative procedures. Its high purity (≥99.5% assay) ensures consistent results in diverse chemical applications and research protocols.

02 /Properties

Molecular weight	207.29
Empirical formula	C8H17NO3S
Assay	≥99.5% (T)
Solubility	H2O: soluble0.5 M at 20 °C, clear, colorless
pH	3.0-5.0 (25 °C, 0.5 M in H2O)
Loss on drying	≤0.5% loss on drying, 110 °C
Impurities tested	insoluble matter, passes filter test

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36
Safety statements (S)	26
Anion traces	chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤500 mg/kg
Ignition residue	≤0.05%

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

103-47-9

MDL number

MFCD00003835

PubChem substance

24892541

Beilstein registry

2967601

05 /Additional specifications

Pka 25 &#X00b0;C	9.3
Market Segment	Diagnostic Assay Manufacturing
Uv Absorption	λ: 260 nm Amax: 0.08λ: 280 nm Amax: 0.05
Useful Ph Range	8.6 - 10.0

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is CHES primarily used for?

CHES is primarily used in diagnostic assay manufacturing and as a biological buffer in biochemical research due to its effective buffering capacity in the useful pH range of 8.6 - 10.0.

What are the CAS number and chemical formula for CHES?

The CAS number for CHES is 103-47-9, and its empirical formula (Hill notation) is C8H17NO3S.

What grade and purity does Tech Serve Solutions supply for CHES?

Tech Serve Solutions supplies CHES with an assay of ≥99.5% (T). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should CHES be handled safely?

CHES is classified as a warning substance (GHS07) and is known to cause serious eye irritation (H319). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used when handling. Ensure adequate ventilation. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do, continuing rinsing (P305 + P351 + P338).

Is CHES available for international export?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including CHES, and can fulfil international export requirements.

How can I request a quote or sample for CHES?

To request a quote or a sample of CHES, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.