CGS-21680 hydrochloride hydrate
CGS-21680 hydrochloride hydrate (CAS: 124182-57-6) is a chemical compound with the formula C23H29N7O6 · HCl · xH2O and a molecular weight of 535.98 g/mol on an anhydrous basis. This white solid, supplied with an assay of ≥98% (HPLC), is primarily utilised as a research tool in cell biology and neuroscience, particularly for investigating adenosine receptors and cell signalling pathways. It is a highly specific agonist for adenosine receptors.
- IUPAC
- 2-p-(2-Carboxyethyl)phenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride hydrate
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Adenosine Receptor Research
CGS-21680 hydrochloride hydrate serves as a selective agonist for adenosine receptors, making it invaluable for studying receptor function, downstream signalling pathways, and their role in various physiological processes. Its application is crucial in understanding neurotransmission and cellular responses modulated by adenosine.
Cellular Signalling Studies
This compound aids in the investigation of cellular signalling cascades initiated by adenosine receptor activation. Researchers use it to probe pathways involved in cell growth, differentiation, and metabolic regulation, particularly within neuroscience and related fields.
Neuroscience Research Tool
As a bioactive small molecule, CGS-21680 hydrochloride hydrate is employed in neuroscience research to explore the effects of adenosine receptor agonism on neuronal activity, synaptic plasticity, and behaviour. It helps elucidate the complex roles of purinergic signalling in the central nervous system.
| Molecular weight | 535.98 (anhydrous basis) |
|---|---|
| Empirical formula | C23H29N7O6 · HCl · xH2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >10 mg/mL45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble20 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADORA2A(135), ADORA2B(136) |
|---|---|
| Storage Condition | desiccated |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CGS-21680 hydrochloride hydrate used for?
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CGS-21680 hydrochloride hydrate is primarily used as a selective agonist in research for studying adenosine receptors (ADORA2A, ADORA2B), cellular signalling pathways, and neurotransmission, particularly within neuroscience and cell biology.
What is the CAS number and chemical formula?
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The CAS number for the anhydrous form is 124182-57-6. The chemical formula is C23H29N7O6 · HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies CGS-21680 hydrochloride hydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should CGS-21680 hydrochloride hydrate be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for comprehensive handling information. It is classified with WGK Germany 3.
How is CGS-21680 hydrochloride hydrate shipped and exported?
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This product is shipped and exported as a white solid, typically stored desiccated at -20°C, to maintain its integrity during transit and storage.
How can I request a sample or quote?
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To request a sample or a quote for CGS-21680 hydrochloride hydrate, please contact our sales team through our website or by calling us directly.
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