Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate
Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate (CAS: 156748-67-3) is an organophosphorus compound with the linear formula CF3CH(OH)P(O)(OC2H5)2 and a molecular weight of 236.13 g/mol. This chemical serves as a valuable synthetic reagent, particularly in C-C bond formation through olefination reactions. Its structure makes it a useful building block in organic synthesis, offering a trifluoroethoxyphosphonate moiety for incorporation into target molecules.
- Synonyms
- 156748-67-3, CF3CH(OH)P(O)(OC2H5)2
C-C Bond Formation
This compound is employed in organic synthesis for the creation of carbon-carbon bonds. It functions as a reagent in reactions that build molecular complexity.
Horner-Wadsworth-Emmons Reagent
As a phosphonate ester, it can participate in Horner-Wadsworth-Emmons reactions. This olefination method is critical for synthesizing alkenes from carbonyl compounds.
Chemical Synthesis
It serves as a versatile intermediate or reagent in various chemical syntheses, allowing for the introduction of trifluoro-substituted hydroxyethyl groups.
Olefination Reactions
The compound is specifically useful in olefination processes, enabling the stereoselective formation of double bonds in organic molecules.
| Molecular weight | 236.13 |
|---|---|
| Linear formula | CF3CH(OH)P(O)(OC2H5)2 |
| Assay | 97% |
| Melting point | 59-63 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 21/22-36/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate used for?
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Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate is used in organic synthesis, primarily for C-C bond formation and in olefination reactions such as the Horner-Wadsworth-Emmons reaction, to create alkenes.
What is the CAS number and formula for Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate?
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The CAS number is 156748-67-3 and the linear formula is CF3CH(OH)P(O)(OC2H5)2.
What grade and purity does Tech Serve Solutions supply for Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate?
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Tech Serve Solutions supplies Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate with a purity of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations when handling this chemical?
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This compound is classified as a Warning. It is harmful if swallowed (H302), harmful in contact with skin (H312), causes skin irritation (H315), and causes serious eye irritation (H319). Always handle with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area. Avoid contact with skin, eyes, and clothing. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
How is Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate packed and shipped?
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This chemical is carefully packed according to international shipping regulations to ensure safe transit. We export globally to researchers and manufacturers.
How can I request a quote or sample?
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Please contact our sales team or use the online form on our website to request a quote or a sample of Diethyl (2,2,2-trifluoro-1-hydroxyethyl)phosphonate.
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