Diethoxymethyl acetate
Diethoxymethyl acetate (CAS: 14036-06-7) is a chemical compound with the linear formula CH3COOCH(OCH2CH3)2 and a molecular weight of 162.18 g/mol. This ester is utilised as a building block in organic synthesis, particularly in the preparation of complex molecules. Its properties make it a valuable reagent for chemical research and development, contributing to advancements in various scientific fields requiring precise chemical structures.

Synthesis of Nucleoside Analogues
Diethoxymethyl acetate has been employed in the synthesis of important nucleoside derivatives, specifically D-mannosyl, D-galactosyl, and D-glucosyl theophylline nucleosides. This application highlights its utility in creating molecules with potential biological activity.
Organic Synthesis Building Block
As an ester and a carbonyl compound, diethoxymethyl acetate serves as a versatile building block in organic chemistry. It is suitable for reactions requiring acetal or ester functionalities, facilitating the construction of more complex organic structures.
Chemical Research and Development
This compound is a valuable reagent for academic and industrial research laboratories. Its specific chemical structure allows for diverse synthetic transformations, supporting the development of novel compounds and materials.
| Molecular weight | 162.18 |
|---|---|
| Linear formula | CH3COOCH(OCH2CH3)2 |
| Assay | 96% |
| Density | 0.993 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.399(lit.) |
| Storage temperature | 2-8°C |
| Application | Diethoxymethyl acetate was used in the synthesis of D-mannosyl, D-galactosyl and D-glucosyl theophylline nucleosides1. |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 27 °C / 80.6 °F |
| Transport (UN / ADR) | UN 3272 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethoxymethyl acetate used for?
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Diethoxymethyl acetate is primarily used as a building block in organic synthesis, notably in the preparation of D-mannosyl, D-galactosyl, and D-glucosyl theophylline nucleosides.
What is the CAS number and formula for Diethoxymethyl acetate?
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The CAS number for Diethoxymethyl acetate is 14036-06-7, and its linear formula is CH3COOCH(OCH2CH3)2.
What grade and purity does Tech Serve Solutions supply for Diethoxymethyl acetate?
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Tech Serve Solutions supplies Diethoxymethyl acetate with a purity of 96% (assay). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Diethoxymethyl acetate be handled safely?
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Diethoxymethyl acetate is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and ensure adequate ventilation. Store in a cool, well-ventilated place away from heat and ignition sources.
How is Diethoxymethyl acetate packed and shipped?
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Diethoxymethyl acetate is packed according to industry standards for chemical reagents and is exported globally by Tech Serve Solutions, adhering to all relevant transport regulations, including UN 3272.
How can I request a sample or quote for Diethoxymethyl acetate?
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To request a sample or a quote for Diethoxymethyl acetate, please contact the Tech Serve Solutions sales team through our website or by calling our customer service line.
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