2-(Diisopropylphosphino)ethylamine
2-(Diisopropylphosphino)ethylamine (CAS 1053657-14-9), with the molecular formula C8H20NP and a molecular weight of 161.22 g/mol, is a key aminophosphine ligand. It is primarily utilised as a reactant in the synthesis of specialised ruthenium hydrogenation catalysts. Its chemical structure and properties make it valuable in various catalytic applications within organic synthesis and inorganic chemistry.
- IUPAC
- 2-[Bis(1-methylethyl)phosphino]ethanamine
Synthesis of Ruthenium Hydrogenation Catalysts
2-(Diisopropylphosphino)ethylamine serves as a crucial building block for the preparation of ruthenium-based hydrogenation catalysts. These catalysts are employed in various reduction reactions within organic synthesis.
Asymmetric Synthesis
As an aminophosphine ligand, this compound is valuable in asymmetric synthesis. It can be incorporated into chiral catalyst systems to control stereochemistry in chemical transformations.
Catalysis and Inorganic Chemistry
Its phosphine and amine functionalities make it a versatile ligand for transition metal complexes. This is applicable in diverse areas of catalysis and inorganic coordination chemistry.
Chemical Synthesis Reagent
Beyond catalyst preparation, 2-(Diisopropylphosphino)ethylamine can act as a reagent in broader chemical synthesis pathways, leveraging its unique bidentate coordinating capabilities.
| Molecular weight | 161.22 |
|---|---|
| Empirical formula | C8H20NP |
| Density | 0.872 g/mL at 25 °C |
| Refractive index | n20/D 1.489 |
| Concentration | 10 wt. % in THF |
| Application | Reactant for synthesis of ruthenium hydrogenation catalysts1 |
Hazard statements
- H226Flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H314Causes severe skin burns and eye damage
Precautionary statements
- P222Do not allow contact with air
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P422
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 43 °C / 109.4 °F |
| Transport (UN / ADR) | UN 2845 4.2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 10-17-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Diisopropylphosphino)ethylamine used for?
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2-(Diisopropylphosphino)ethylamine is primarily used as a reactant in the synthesis of ruthenium hydrogenation catalysts and finds applications in asymmetric synthesis and broader chemical synthesis due to its properties as an aminophosphine ligand.
What are the CAS number and molecular formula for 2-(Diisopropylphosphino)ethylamine?
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The CAS number for 2-(Diisopropylphosphino)ethylamine is 1053657-14-9, and its molecular formula is C8H20NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Diisopropylphosphino)ethylamine at a concentration of 10 wt. % in THF. We do not represent this product as USP, BP, or EP grade; it is intended for research and laboratory use.
What are the key safety considerations when handling 2-(Diisopropylphosphino)ethylamine?
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2-(Diisopropylphosphino)ethylamine is a flammable liquid (H226) and pyrophoric (H250), meaning it can ignite spontaneously in air. It also causes severe skin burns and eye damage (H314). Strict handling procedures, including inert atmosphere techniques and appropriate personal protective equipment (gloves, eye protection, respirator), are essential.
How is 2-(Diisopropylphosphino)ethylamine packed and shipped?
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This product is classified as UN 2845, Hazard Class 4.2, for transport. It is handled under specific conditions due to its pyrophoric nature and shipped according to relevant dangerous goods regulations.
How can I request a quote or sample for 2-(Diisopropylphosphino)ethylamine?
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To request a quote or sample, please contact our sales team via the website or provide your inquiry details, including the product name and CAS number, through our online portal.
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