(Cyanomethyl)trimethylammonium iodide
(Cyanomethyl)trimethylammonium iodide (CAS 82272-28-4) is a quaternary ammonium salt with the linear formula ((CH3)3NCH2CN)+ I-. It serves as a valuable reagent in organic synthesis, particularly for C-C bond formation. With a molecular weight of 226.06 g/mol, this compound is supplied by Tech Serve Solutions at a purity of 97%, making it suitable for various chemical synthesis and research applications.
- IUPAC
- (N-Iodo-N,N,N-trimethylamino)acetonitrile,1-Cyano-N,N,N-trimethyl-methanaminium iodide,2-(Dimethylamino)acetonitrile methyl iodide
- Synonyms
- (N-Iodo-N,N,N-trimethylamino)acetonitrile1-Cyano-N,N,N-trimethyl-methanaminium iodide2-(Dimethylamino)acetonitrile methyl iodide

Vicarious Nucleophilic Substitution (VNS)
This compound is a key reactant in Vicarious Nucleophilic Substitution (VNS) reactions. VNS is a powerful method for introducing substituents onto aromatic and heteroaromatic rings, enabling complex molecule synthesis.
C-C Bond Formation
As a reagent involved in C-C bond formation, (Cyanomethyl)trimethylammonium iodide facilitates the creation of new carbon-carbon linkages. This is fundamental in constructing larger organic molecules from smaller precursors.
Chemical Synthesis
Utilised in general chemical synthesis, this reagent aids in the development and production of diverse organic compounds. Its specific reactivity makes it useful for targeted synthetic strategies.
Synthetic Reagents
The compound falls under the category of synthetic reagents, employed by researchers and chemists to perform specific chemical transformations. Its structure lends itself to various synthetic methodologies.
| Molecular weight | 226.06 |
|---|---|
| Linear formula | ((CH3)3NCH2CN)+ I- |
| Assay | 97% |
| Application | Reactant for:• Vicarious nucleophilic substitution (VNS) reactions1 |
| Melting point | 212-216 °C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Cyanomethyl)trimethylammonium iodide used for?
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(Cyanomethyl)trimethylammonium iodide is primarily used as a reactant in Vicarious Nucleophilic Substitution (VNS) reactions and for C-C bond formation in general chemical synthesis.
What is the CAS number and chemical formula?
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The CAS number for (Cyanomethyl)trimethylammonium iodide is 82272-28-4. Its linear formula is ((CH3)3NCH2CN)+ I-.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Cyanomethyl)trimethylammonium iodide with an assay of 97%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should (Cyanomethyl)trimethylammonium iodide be handled safely?
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Due to its hazardous nature (Danger, H301-H315-H319-H335), handle with extreme care. Use in a well-ventilated area and wear appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator cartridge (EN 143). Seek immediate medical attention if ingested or if contact occurs.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (Cyanomethyl)trimethylammonium iodide. We can arrange for its shipment worldwide.
How can I request a sample or quote?
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To request a sample or a quote for (Cyanomethyl)trimethylammonium iodide, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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