(Cyclohexylmethyl)magnesium bromide solution
(Cyclohexylmethyl)magnesium bromide solution (CAS 35166-78-0) is an organometallic reagent with a molecular weight of 201.39 g/mol. This Grignard reagent is a flammable and corrosive liquid, used in various chemical synthesis applications. It is notably employed in polymerization reactions, rearrangements of cyclopropanes, and cycloisomerization processes. Furthermore, it serves as a key reactant in the synthesis of biologically significant molecules like proteasome inhibitors and antitumor agents.
Polymerisation Reactions
This reagent is involved in the isomerisation polymerisation of alkenylcyclohexanes, contributing to the formation of specific polymer structures.
Organic Synthesis Transformations
It facilitates intramolecular rearrangements of vinylidenecyclopropanes and cycloisomerisation of cyclic and acyclic enynes, enabling complex molecular construction.
Biologically Active Molecule Synthesis
The compound is used in the synthesis of dipeptidyl boronic acid proteasome inhibitors and substituted 1,3-dihydroindole-2-ones with reported antitumor effects.
Nucleoside Analog Inhibitor Synthesis
It plays a role in the synthesis of sulfur-free transition state nucleoside analog inhibitors for methylthioadenosine nucleosidase and phosphorylase.
| Molecular weight | 201.39 |
|---|---|
| Empirical formula | C7H13BrMg |
| Density | 0.966 g/mL at 25 °C |
| Application | Reactant involved in:• Isomerization polymerization of alkenylcyclohexanes1• Intramolecular rearrangements of vinylidenecyclopropanes2• Cycloisomerization of cyclic and acyclic enynes3Additionally reactant involved in synthesis of biologically active molecules including:• Dipeptidyl boronic acid proteasome inhibitors4• Substituted 1,3-dihydroindole-2-ones with antitumor effects5• Sulfur-free transition state nucleoside analog inhibitors of methylthioadenosine nucleosidase and phosphorylase6 |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -20 °C / -4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Cyclohexylmethyl)magnesium bromide solution used for?
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(Cyclohexylmethyl)magnesium bromide solution is used as a reactant in polymerisation, organic transformations like rearrangements and cycloisomerisations, and in the synthesis of biologically active molecules, including proteasome inhibitors and antitumor agents.
What is the CAS number and formula for (Cyclohexylmethyl)magnesium bromide solution?
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The CAS number is 35166-78-0. The empirical formula is C7H13BrMg.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Cyclohexylmethyl)magnesium bromide solution typically as a technical or research grade. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated otherwise in the product specifications.
What are the primary safety concerns when handling this product?
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This product is highly flammable (flash point -20 °C) and corrosive, reacting violently with water and may form explosive peroxides. Appropriate personal protective equipment (gloves, eye protection) and handling procedures in a well-ventilated area or fume hood are essential. Refer to the Safety Data Sheet for detailed handling and emergency procedures.
How is (Cyclohexylmethyl)magnesium bromide solution packaged, shipped, and exported?
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This reagent is carefully packaged in compliance with international regulations for hazardous materials. Tech Serve Solutions has extensive experience in exporting chemicals globally.
How can I request a sample or obtain a quote?
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To request a sample or obtain a quote for (Cyclohexylmethyl)magnesium bromide solution, please contact our sales team through the website or by phone. Please provide your required quantity and delivery location.
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