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Calpain Inhibitor I

CAS 110044-82-1C20H37N3O4Chemical Synthesis

Calpain Inhibitor I (CAS: 110044-82-1) is a critical biochemical reagent with the molecular formula C20H37N3O4 and a molecular weight of 383.53 g/mol. This compound functions as an effective inhibitor of calpain enzymes, which play vital roles in cellular processes such as muscle proteolysis and apoptosis. It is primarily used in biochemical research and cell biology studies to investigate the function and regulation of calpain activity.

IUPAC
ALLN,Ac-LLnL-CHO,MG-101,N-Acetyl-Leu-Leu-Norleu-al,N-Acetyl-L-leucyl-L-leucyl-L-norleucinal
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Calpain Inhibitor I (C20H37N3O4) — chemical structure, CAS 110044-82-1; Chemistry, fine chemical supplied by Tech Serve Solutions
AldehydesBioactive Small MoleculesBiochemicals and ReagentsBuilding BlocksC-CHC13-C60Carbonyl CompoundsCell BiologyChemical SynthesisEnzyme Inhibitors
01 /Applications

Calpain Enzyme Inhibition

Calpain Inhibitor I serves as a potent inhibitor for calpain proteases, enabling researchers to study their physiological and pathological roles. This is crucial for understanding cellular signaling pathways and disease mechanisms involving calpain dysregulation.

Cell Biology Research

In cell biology, this inhibitor is employed to probe the involvement of calpains in processes like cell death, differentiation, and protein turnover. It helps elucidate the specific functions mediated by these calcium-dependent proteases.

Biochemical Assays

It is utilized in biochemical assays to characterize enzyme kinetics and to validate potential therapeutic targets related to calpain activity. Its specific inhibitory action makes it a valuable tool for enzyme studies.

02 /Properties
Molecular weight383.53
Empirical formulaC20H37N3O4
Assay≥97% (TLC)
SolubilityDMSO: solubleethanol: soluble
Storage temperature−20°C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
110044-82-1
MDL number
MFCD00065505
Beilstein registry
7656053
05 /Additional specifications
Gene Informationhuman ... CAPN1(823), CTSB(1508), PSMA1(5682)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Calpain Inhibitor I used for?

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Calpain Inhibitor I is used in biochemical research and cell biology to inhibit calpain enzymes, aiding in the study of cellular processes regulated by these proteases.

What is the CAS number and molecular formula for Calpain Inhibitor I?

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The CAS number is 110044-82-1, and the molecular formula is C20H37N3O4.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Calpain Inhibitor I with a purity of ≥97% (TLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should Calpain Inhibitor I be handled and stored?

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Handle Calpain Inhibitor I with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store at −20°C. Refer to the safety data sheet for comprehensive handling guidelines. Its WGK Germany classification is 3.

How is this chemical packed, shipped, and exported?

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Calpain Inhibitor I is carefully packaged to maintain its integrity during transit and is exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations.

How can I request a sample or quote for Calpain Inhibitor I?

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To request a sample or a quote for Calpain Inhibitor I, please contact the Tech Serve Solutions sales team through our website or by calling our direct line.

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