Calpain Inhibitor I
Calpain Inhibitor I (CAS: 110044-82-1) is a critical biochemical reagent with the molecular formula C20H37N3O4 and a molecular weight of 383.53 g/mol. This compound functions as an effective inhibitor of calpain enzymes, which play vital roles in cellular processes such as muscle proteolysis and apoptosis. It is primarily used in biochemical research and cell biology studies to investigate the function and regulation of calpain activity.
- IUPAC
- ALLN,Ac-LLnL-CHO,MG-101,N-Acetyl-Leu-Leu-Norleu-al,N-Acetyl-L-leucyl-L-leucyl-L-norleucinal

Calpain Enzyme Inhibition
Calpain Inhibitor I serves as a potent inhibitor for calpain proteases, enabling researchers to study their physiological and pathological roles. This is crucial for understanding cellular signaling pathways and disease mechanisms involving calpain dysregulation.
Cell Biology Research
In cell biology, this inhibitor is employed to probe the involvement of calpains in processes like cell death, differentiation, and protein turnover. It helps elucidate the specific functions mediated by these calcium-dependent proteases.
Biochemical Assays
It is utilized in biochemical assays to characterize enzyme kinetics and to validate potential therapeutic targets related to calpain activity. Its specific inhibitory action makes it a valuable tool for enzyme studies.
| Molecular weight | 383.53 |
|---|---|
| Empirical formula | C20H37N3O4 |
| Assay | ≥97% (TLC) |
| Solubility | DMSO: solubleethanol: soluble |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CAPN1(823), CTSB(1508), PSMA1(5682) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Calpain Inhibitor I used for?
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Calpain Inhibitor I is used in biochemical research and cell biology to inhibit calpain enzymes, aiding in the study of cellular processes regulated by these proteases.
What is the CAS number and molecular formula for Calpain Inhibitor I?
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The CAS number is 110044-82-1, and the molecular formula is C20H37N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Calpain Inhibitor I with a purity of ≥97% (TLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Calpain Inhibitor I be handled and stored?
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Handle Calpain Inhibitor I with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store at −20°C. Refer to the safety data sheet for comprehensive handling guidelines. Its WGK Germany classification is 3.
How is this chemical packed, shipped, and exported?
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Calpain Inhibitor I is carefully packaged to maintain its integrity during transit and is exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations.
How can I request a sample or quote for Calpain Inhibitor I?
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To request a sample or a quote for Calpain Inhibitor I, please contact the Tech Serve Solutions sales team through our website or by calling our direct line.
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