H-7

CAS 84477-87-2C14H17N3O2SBiochemicals & Reagents

H-7 (CAS: 84477-87-2), with the molecular formula C14H17N3O2S and a molecular weight of 291.37 g/mol, is a valuable research chemical. It functions as a potent inhibitor of protein kinase A (PKA) and protein kinase C (PKC), along with other serine/threonine kinases. This compound is instrumental in biochemical research, particularly in studies of cell signalling pathways and neuroscience. Its specific inhibitory action makes it a crucial tool for investigating cellular processes regulated by kinase activity.

IUPAC: 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine,Isoquinoline-5-sulfonic 2-methyl-1-piperazide
Synonyms: 1-(5-Isoquinolinesulfonyl)-2-methylpiperazineIsoquinoline-5-sulfonic 2-methyl-1-piperazide

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H-7 (C14H17N3O2S) — chemical structure, CAS 84477-87-2; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand SubstratesKinase/Phosphatase BiologyP to Q

01 /Applications

Protein Kinase Inhibition

H-7 is widely employed as an inhibitor for protein kinase A (PKA) and protein kinase C (PKC). It also inhibits other serine/threonine kinases, making it a versatile tool in biochemical research for dissecting kinase-dependent signalling pathways.

Cell Signalling Research

This compound aids in the study of cellular processes regulated by protein kinases. Researchers use H-7 to investigate the roles of PKA and PKC in various cellular functions and signal transduction cascades.

Neuroscience Studies

H-7 serves as a research reagent in neuroscience to explore the involvement of specific kinases in neuronal function and signalling. Its inhibitory properties help elucidate the complex mechanisms within the nervous system.

02 /Properties

Molecular weight	291.37
Empirical formula	C14H17N3O2S
Solubility	ethanol: soluble20 mg/mL1 M HCl: soluble5 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

84477-87-2

MDL number

MFCD00063403

PubChem substance

24896097

Beilstein registry

5482740

05 /Additional specifications

Gene Information	human ... CALCRL(10203)rat ... Calcrl(25029)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is H-7 used for?

H-7 is primarily used as a research chemical for inhibiting protein kinase A (PKA) and protein kinase C (PKC), and other serine/threonine kinases. It is valuable for studying cell signalling, neuroscience, and biochemical pathways.

What is the CAS number and formula for H-7?

The CAS number for H-7 is 84477-87-2, and its molecular formula is C14H17N3O2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies H-7 as a research-grade chemical. The specific purity is not detailed in the available data, and TSS does not represent this product as meeting USP, BP, or EP pharmacopoeia standards.

How should H-7 be handled and stored safely?

Handle H-7 with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the chemical at 2-8°C.

Is H-7 a controlled substance?

The provided data does not indicate that H-7 is a controlled substance.

How can I request a quote or sample for H-7?

To request a quote or sample of H-7, please contact Tech Serve Solutions directly through our website or sales representatives.

How is H-7 packed, shipped, and exported?

Tech Serve Solutions packs and ships H-7 adhering to all necessary regulations for chemical handling and transport, including international export standards for research chemicals.