HA-100
HA-100 (CAS: 84468-24-6; C13H15N3O2S) is a chemical compound with a molecular weight of 277.34 g/mol. It functions as an inhibitor, notably targeting protein kinases like Protein Kinase A (PKA), Protein Kinase C (PKC), and Myosin Light Chain Kinase (MLCK). This makes it a valuable tool in biochemical research for studying cellular signaling pathways and enzyme activity in various biological systems.
- IUPAC
- 1-(5-Isoquinolinesulfonyl)piperazine hydrochloride
- Synonyms
- 1-(5-Isoquinolinesulfonyl)piperazine hydrochloride
Enzyme Inhibition Research
HA-100 serves as a selective inhibitor for key kinases such as PKA, PKC, and MLCK. Researchers utilise it to investigate the roles of these enzymes in cellular processes and signalling cascades.
Cellular Signaling Studies
As a potent inhibitor, HA-100 is employed to modulate and study signal transduction pathways influenced by PKA, PKC, and MLCK activity in various cell types.
Biochemical Reagent
This compound is a useful biochemical reagent for in vitro experiments aimed at understanding enzyme kinetics and the effects of kinase inhibition on biological systems.
| Molecular weight | 277.34 |
|---|---|
| Empirical formula | C13H15N3O2S |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... MYLK(4638), MYLK2(85366) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is HA-100 used for?
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HA-100 is primarily used in research as an inhibitor for protein kinases such as Protein Kinase A (PKA), Protein Kinase C (PKC), and Myosin Light Chain Kinase (MLCK), aiding in the study of cellular signaling pathways.
What is the CAS number and formula for HA-100?
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The CAS number for HA-100 is 84468-24-6, and its empirical formula is C13H15N3O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies HA-100 as a research-grade chemical. The exact purity is not specified in the provided data; TSS does not represent this product as USP, BP, or EP grade.
How should HA-100 be handled and stored?
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HA-100 requires careful handling due to its irritant properties (H315, H319, H335). Use a dust mask (type N95), eyeshields, and gloves. Store at -20°C. Ensure adequate ventilation and avoid dust formation.
Is HA-100 a controlled substance?
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The provided data does not indicate that HA-100 is a controlled substance.
How is HA-100 packed, shipped, or exported?
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HA-100 is packed with safety in mind, adhering to regulations for chemical transport. TSS exports fine chemicals globally.
How can I request a sample or quote for HA-100?
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To request a sample or quote for HA-100, please contact the Tech Serve Solutions sales team through our official channels.
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