2,4-Difluorophenyl isothiocyanate
2,4-Difluorophenyl isothiocyanate (CAS: 141106-52-7), with the molecular formula F2C6H3NCS and a molecular weight of 171.17 g/mol, is a specialised organic compound. It functions as a valuable building block in chemical synthesis, particularly within the pharmaceutical and agrochemical sectors. Its difluorophenyl and isothiocyanate functionalities make it suitable for introducing fluorinated aryl motifs into complex molecular structures.
- Synonyms
- F2C6H3NCS
Organic Synthesis Intermediate
This compound serves as a key intermediate in the synthesis of various organic molecules. Its reactive isothiocyanate group readily participates in addition reactions, enabling the construction of heterocyclic compounds and other complex structures.
Pharmaceutical Research
2,4-Difluorophenyl isothiocyanate is utilized in the development of novel pharmaceutical agents. The presence of fluorine atoms can significantly influence the metabolic stability, lipophilicity, and binding affinity of drug candidates.
Agrochemical Development
It finds application in the design and synthesis of new agrochemicals, such as pesticides and herbicides. The difluorophenyl moiety can impart desirable properties to active ingredients.
Material Science
This isothiocyanate derivative may be employed in the development of advanced materials, potentially contributing to polymers or functionalised surfaces due to its specific chemical characteristics.
| Molecular weight | 171.17 |
|---|---|
| Linear formula | F2C6H3NCS |
| Assay | 98% |
| Boiling point | 46-48 °C/0.5 mmHg(lit.) |
| Density | 1.349 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.598(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluorophenyl isothiocyanate used for?
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2,4-Difluorophenyl isothiocyanate is primarily used as a versatile building block in organic synthesis, particularly for the preparation of pharmaceutical intermediates, agrochemicals, and potentially in material science applications.
What are the CAS number and formula for 2,4-Difluorophenyl isothiocyanate?
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The CAS number is 141106-52-7 and the linear formula is F2C6H3NCS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Difluorophenyl isothiocyanate with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety concerns when handling 2,4-Difluorophenyl isothiocyanate?
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This compound is classified with GHS07 symbol and carries a Warning signal word. It is associated with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, is essential.
How is 2,4-Difluorophenyl isothiocyanate packed and shipped?
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2,4-Difluorophenyl isothiocyanate is carefully packed for shipment to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 2,4-Difluorophenyl isothiocyanate?
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To request a sample or a quotation for 2,4-Difluorophenyl isothiocyanate, please contact our sales department through the website or by phone.
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