2,4-Difluorophenyl isocyanate
2,4-Difluorophenyl isocyanate (CAS 59025-55-7), with a molecular weight of 155.10 g/mol, is a key organic fluorinated building block. This compound is utilised in organic synthesis for introducing the 2,4-difluorophenyl group into various molecules. Its reactive isocyanate functionality makes it valuable for creating amides, ureas, and other derivatives, finding application in the development of pharmaceuticals and advanced materials.
- Synonyms
- F2C6H3NCO
Pharmaceutical Intermediate
Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). The difluorophenyl moiety can enhance metabolic stability and binding affinity of drug candidates.
Agrochemical Synthesis
Employed in the preparation of novel pesticides and herbicides. The fluorine atoms can influence the biological activity and environmental persistence of agrochemical compounds.
Material Science
Used in the development of specialty polymers and functional materials. The incorporation of fluorinated aromatic rings can impart desirable properties such as thermal stability and hydrophobicity.
Organic Synthesis Reagent
A versatile reagent for introducing the 2,4-difluorophenyl group via reactions characteristic of isocyanates, such as addition reactions with nucleophiles.
| Molecular weight | 155.10 |
|---|---|
| Linear formula | F2C6H3NCO |
| Assay | 99% |
| Grade | purum |
| Boiling point | 42 °C/6 mmHg(lit.) |
| Density | 1.309 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.490(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Flash point | 55 °C / 131 °F |
|---|---|
| Transport (UN / ADR) | UN 2478 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluorophenyl isocyanate used for?
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2,4-Difluorophenyl isocyanate is used as a building block in organic synthesis, particularly for preparing pharmaceuticals, agrochemicals, and advanced materials. Its reactive isocyanate group allows for the introduction of the 2,4-difluorophenyl moiety into various molecular structures.
What is the CAS number and formula for 2,4-Difluorophenyl isocyanate?
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The CAS number is 59025-55-7, and its linear formula is F2C6H3NCO. The molecular weight is 155.10 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Difluorophenyl isocyanate with an assay of 99% and a 'purum' grade. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2,4-Difluorophenyl isocyanate be handled safely?
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2,4-Difluorophenyl isocyanate is a flammable liquid and vapour (H226). It is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It causes skin (H315) and serious eye irritation (H319). It may cause respiratory irritation (H335) and an allergic skin reaction (H317, not in provided data but typical for isocyanates). It can also cause allergy or asthma symptoms or breathing difficulties if inhaled (H334). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding ignition sources.
How is 2,4-Difluorophenyl isocyanate packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports 2,4-Difluorophenyl isocyanate according to international regulations for hazardous materials, ensuring safe and compliant transit to global destinations.
How can I request a sample or quote for 2,4-Difluorophenyl isocyanate?
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To request a sample or a quote for 2,4-Difluorophenyl isocyanate, please contact our sales team through the website or by phone.
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