2,4-Difluorophenylacetonitrile
2,4-Difluorophenylacetonitrile (CAS: 656-35-9) is a fluorinated organic compound with the molecular formula F₂C₆H₃CH₂CN and a molecular weight of 153.13 g/mol. It serves as a valuable building block in organic synthesis, particularly within the fields of medicinal chemistry and materials science. Its structure, featuring two fluorine atoms on the phenyl ring and a nitrile group, allows for diverse chemical transformations, making it a key intermediate for creating complex molecules.
- Synonyms
- 2,4-DifluorophenylacetonitrileF2C6H3CH2CN
Synthesis of Complex Organic Molecules
2,4-Difluorophenylacetonitrile is used as a precursor in the multi-step synthesis of sophisticated organic compounds. It has been specifically noted for its role in preparing novel pentenenitrile derivatives, which can serve as intermediates in pharmaceutical research.
Pharmaceutical Intermediates
The unique difluorophenylacetonitrile structure makes it an attractive starting material for developing new pharmaceutical agents. Its incorporation into molecular structures can influence pharmacokinetic properties and biological activity.
Research and Development
As a versatile building block, this compound is frequently employed in academic and industrial research laboratories. It facilitates the exploration of new chemical reactions and the development of novel fluorinated compounds with potential applications.
| Molecular weight | 153.13 |
|---|---|
| Linear formula | F2C6H3CH2CN |
| Assay | 97% |
| Density | 1.249 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.48(lit.) |
| Application | 2,4-Difluorophenylacetonitrile has been used in the preparation of (E,Z)-(4S)-4-tert-butoxycarbonylamino-3-hydroxy-2-(3,5-difluorophenyl)-5-phenyl-2pentenenitrile1. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluorophenylacetonitrile used for?
+
2,4-Difluorophenylacetonitrile is used as a building block in organic synthesis, particularly for preparing complex molecules and pharmaceutical intermediates. It has been employed in the synthesis of specific pentenenitrile derivatives.
What is the CAS number and chemical formula for 2,4-Difluorophenylacetonitrile?
+
The CAS number is 656-35-9, and the linear chemical formula is F₂C₆H₃CH₂CN.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,4-Difluorophenylacetonitrile with a minimum assay of 97%. TSS does not represent this product as USP, BP, or EP grade; it is supplied for research and general laboratory use.
How should 2,4-Difluorophenylacetonitrile be handled safely?
+
2,4-Difluorophenylacetonitrile is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin, eye, and respiratory irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., multi-purpose combination respirator cartridge or type ABEK respirator filter), must be used. Handle in a well-ventilated area.
Is 2,4-Difluorophenylacetonitrile a controlled substance?
+
The provided data does not indicate that 2,4-Difluorophenylacetonitrile is a controlled substance.
How is 2,4-Difluorophenylacetonitrile packed, shipped, and exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are packed and shipped in accordance with international regulations for hazardous materials, such as NA 1993, PGIII.
How can I request a quote or sample for 2,4-Difluorophenylacetonitrile?
+
To request a quote or sample, please contact the TSS sales department through our official website or by calling our customer service line.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis