2,4-Difluorobenzylzinc bromide solution
2,4-Difluorobenzylzinc bromide solution (CAS 307496-26-0) is an organozinc halide reagent supplied by Tech Serve Solutions. With a molecular weight of 272.41 g/mol and a concentration of 0.5 M in THF, this solution is primarily utilised in organic synthesis. It is commonly employed in cross-coupling reactions and as a nucleophilic source of the 2,4-difluorobenzyl group, enabling the formation of new carbon-carbon bonds in complex molecule construction.
- Synonyms
- F2C6H3CH2ZnBr
Organic Synthesis
Utilised as a key intermediate in various organic transformations, particularly in the construction of complex organic molecules. Its organozinc nature makes it valuable for carbon-carbon bond formation.
Cross-Coupling Reactions
Serves as a nucleophilic coupling partner in transition-metal catalysed cross-coupling reactions, such as Negishi coupling. This facilitates the introduction of the 2,4-difluorobenzyl moiety into target structures.
Pharmaceutical Intermediate Synthesis
Applicable in the synthesis of pharmaceutical intermediates where the 2,4-difluorobenzyl group is a desired structural element. This includes the development of novel drug candidates.
| Molecular weight | 272.41 |
|---|---|
| Linear formula | F2C6H3CH2ZnBr |
| Density | 0.995 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluorobenzylzinc bromide solution primarily used for?
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2,4-Difluorobenzylzinc bromide solution is primarily used in organic synthesis for the construction of carbon-carbon bonds, particularly in cross-coupling reactions, and as an intermediate in the synthesis of pharmaceuticals.
What is the CAS number and chemical formula for 2,4-Difluorobenzylzinc bromide solution?
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The CAS number is 307496-26-0 and the linear formula is F₂C₆H₃CH₂ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Difluorobenzylzinc bromide solution at a concentration of 0.5 M in THF. TSS does not represent this product as USP, BP, or EP grade.
How should 2,4-Difluorobenzylzinc bromide solution be handled safely?
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This product is highly flammable and may form explosive peroxides. It is an irritant to the eyes and respiratory system and is suspected of causing cancer. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet for full details.
How is 2,4-Difluorobenzylzinc bromide solution packed and shipped?
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2,4-Difluorobenzylzinc bromide solution is shipped as a UN 2056, Class 3 material, Packing Group II. Specific packaging will be in accordance with transportation regulations.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (307496-26-0).
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