Clozapine
Clozapine (CAS 5786-21-0), with the molecular formula C18H19ClN4 and a molecular weight of 326.82 g/mol, is a premium quality chemical compound. It is primarily recognised for its role as a dopamine antagonist and its applications in neuroscience research. Clozapine is employed in various biochemical and cell biology studies, serving as a valuable tool in understanding cellular signaling pathways and neurotransmitter systems.
- IUPAC
- 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine

Neuroscience Research
Clozapine acts as a dopamine antagonist, making it a critical research chemical for studying neurotransmitter systems and their role in neurological processes. It is used to investigate dopamine receptor activity and related signaling cascades.
Cell Biology Studies
As a bioactive small molecule, Clozapine is utilized in cell biology to explore cellular functions and signaling pathways. Its interactions with specific cellular targets provide insights into cellular mechanisms.
Drug Discovery and Development
Clozapine is recognised as an approved therapeutic and drug candidate, serving as a reference compound or tool in the development of new pharmaceutical agents targeting similar pathways.
| Molecular weight | 326.82 |
|---|---|
| Empirical formula | C18H19ClN4 |
| Solubility | ethanol: soluble1 mg/mL0.1 M HCl: soluble30 mg/mLDMSO: soluble4.8 mg/mL |


Hazard statements
- H301Toxic if swallowed
- H341Suspected of causing genetic defects
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P281Use personal protective equipment as required
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-22-68 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Clozapine used for?
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Clozapine is primarily used in neuroscience research as a dopamine antagonist and in cell biology studies. It is also recognized as an approved therapeutic and drug candidate.
What are the CAS number and formula for Clozapine?
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The CAS number for Clozapine is 5786-21-0, and its molecular formula is C18H19ClN4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Clozapine at a PREMIUM quality level. The exact purity is not specified beyond this designation, and TSS does not represent it as USP, BP, or EP grade.
How should Clozapine be handled safely?
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Clozapine is classified with a GHS Danger signal word. It carries hazard statements H301 (Toxic if swallowed), H341 (Suspected of causing genetic defects), and H361 (Suspected of damaging fertility or the unborn child). Handle with extreme caution, using appropriate personal protective equipment (P281) and following strict safety protocols. Dispose of waste properly (P301 + P310).
Is Clozapine a controlled substance?
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The provided data does not indicate that Clozapine is a controlled substance. However, users should verify its regulatory status in their specific jurisdiction.
How is Clozapine packed, shipped, and exported?
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Clozapine is packed and shipped according to UN 2811, Hazard Class 6.1, Packing Group III regulations, indicating it is a toxic solid. Tech Serve Solutions is experienced in global export of chemicals.
How can I request a sample or quote for Clozapine?
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To request a sample or a quote for Clozapine, please contact the Tech Serve Solutions sales team through our website or by direct inquiry.
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