Cloxacillin sodium salt
Cloxacillin sodium salt (CAS 642-78-4, C19H17ClN3NaO5S, MW: 457.86) is a semisynthetic penicillinase-resistant antibacterial agent. It is primarily used to combat staphylococci strains that produce beta-lactamase, an enzyme conferring resistance to other penicillins. This compound is also utilised in research to investigate factors influencing antibiotic effectiveness, such as pH levels and the impact of various stress conditions on bacterial susceptibility.

Research into Antibiotic Efficacy
Used in laboratory settings to study the influence of environmental factors like pH on the effectiveness of antibiotics. It helps researchers understand how variables can alter the susceptibility of bacteria to antimicrobial agents.
Investigation of Bacterial Stress Responses
Applied in studies examining the effects of oxgall, acid, and hydrogen peroxide on the susceptibility of specific bacterial species, such as Bifidobacteria. This aids in understanding bacterial resilience mechanisms.
Antibacterial Agent Against Beta-Lactamase Producing Bacteria
Serves as a potent antibacterial agent effective against Staphylococcus strains that are resistant to other forms of penicillin due to their production of beta-lactamase enzymes.
| Molecular weight | 457.86 |
|---|---|
| Empirical formula | C19H17ClN3NaO5S |
| Assay | ≥97.0% (HPLC) |
| Solubility | H2O: soluble50 mg/mL, clear, colorless |
| Storage temperature | 2-8°C |
| Impurities tested | ≤5% water |
| Application | Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness1 and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria2. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cloxacillin sodium salt used for?
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Cloxacillin sodium salt is used as a semisynthetic antibacterial agent, particularly effective against Staphylococcus strains that produce beta-lactamase. It is also employed in research to study factors affecting antibiotic effectiveness and bacterial stress responses.
What are the CAS number and formula for Cloxacillin sodium salt?
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The CAS number for Cloxacillin sodium salt is 642-78-4, and its empirical formula is C19H17ClN3NaO5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cloxacillin sodium salt with an assay of ≥97.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Cloxacillin sodium salt be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany classification of 2, indicating it is hazardous.
How is Cloxacillin sodium salt shipped and exported?
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Cloxacillin sodium salt is typically stored at 2-8°C. As a specialist global supplier, Tech Serve Solutions exports fine chemicals worldwide, adhering to all relevant shipping and handling regulations.
How can I request a sample or quote for Cloxacillin sodium salt?
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To request a sample or quote, please contact our sales team through the website or provide your details via the inquiry form, specifying the product name and CAS number.
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