Clobenpropit dihydrobromide
Clobenpropit dihydrobromide (CAS: 145231-45-4) is a chemical compound with the formula C14H17ClN4S · 2HBr and a molecular weight of 470.65 g/mol. This white solid is primarily utilised as a research chemical, notably as a histamine H3 receptor antagonist. Its applications extend to cell biology and neuroscience research, where it serves as a tool for investigating signal transduction pathways and neurotransmission, particularly concerning histamineergic activity.
- IUPAC
- VUF 9153,[(4-Chlorophenyl)methyl]-3-(1H-imidazol-4-yl)propyl ester carbamimidothioic acid dihydrobromide
- Synonyms
- VUF 9153,[(4-Chlorophenyl)methyl]-3-(1H-imidazol-4-yl)propyl ester carbamimidothioic acid dihydrobromide

Histamine H3 Receptor Antagonist Research
Clobenpropit dihydrobromide functions as a selective antagonist for the histamine H3 receptor. It is employed in pharmacological studies to investigate the role of this receptor in various physiological and pathological processes within the central nervous system.
Neuroscience and Cell Signaling Studies
This compound is valuable for researchers studying neurotransmission and cell signalling pathways. Its use helps elucidate the complex mechanisms involving histamine as a neurotransmitter and neuromodulator, contributing to our understanding of neurological functions and disorders.
Bioactive Small Molecule Research
As a bioactive small molecule, Clobenpropit dihydrobromide is utilised in drug discovery and development efforts. It serves as a reference compound or a lead structure in the exploration of new therapeutic agents targeting histamineergic systems.
| Molecular weight | 470.65 |
|---|---|
| Empirical formula | C14H17ClN4S · 2HBr |
| Form | solid |
| Colour | white |
| Solubility | H2O: >20 mg/mLethanol: soluble3.30 mg/mLDMSO: >30 mg/mL |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Clobenpropit dihydrobromide used for?
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Clobenpropit dihydrobromide is primarily used as a research chemical, specifically as a histamine H3 receptor antagonist, in studies related to neuroscience, cell signaling, and the development of potential therapeutic agents.
What are the CAS number and formula for Clobenpropit dihydrobromide?
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The CAS number for Clobenpropit dihydrobromide is 145231-45-4, and its chemical formula is C14H17ClN4S · 2HBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Clobenpropit dihydrobromide as a research grade chemical. Purity information is available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or for human/veterinary use.
How should Clobenpropit dihydrobromide be handled and stored?
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Handle Clobenpropit dihydrobromide with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). It should be stored at 2-8°C.
Is Clobenpropit dihydrobromide a controlled substance?
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Based on the provided data, Clobenpropit dihydrobromide is not indicated as a controlled substance. However, researchers should always comply with local regulations.
How is Clobenpropit dihydrobromide packed, shipped, and exported?
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Clobenpropit dihydrobromide is carefully packed to ensure stability during transit. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all necessary shipping regulations.
How can I request a quote or sample for Clobenpropit dihydrobromide?
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To request a quote or sample for Clobenpropit dihydrobromide, please contact our sales team through the website or by phone, providing your details and requirements.
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