1,1′-Carbonyldipiperidine
1,1′-Carbonyldipiperidine (CAS: 5395-04-0) is a chemical compound with the molecular formula C11H20N2O and a molecular weight of 196.29 g/mol. This compound serves as a key reactant in various sophisticated chemical syntheses. Its applications include the preparation of specialised ligands for copper catalysis, metal complexes with lanthanides, and the formation of novel carbene complexes. It is a valuable building block for researchers in organic and inorganic chemistry.
- IUPAC
- Bis(1-piperidyl) ketone,Bis(pentamethylene)urea,Di-1-piperidinyl-methanone
- Synonyms
- Bis(1-piperidyl) ketoneBis(pentamethylene)ureaDi-1-piperidinyl-methanone

Synthesis of Bis(guanidine) Ligands
1,1′-Carbonyldipiperidine is utilised as a reactant in the synthesis of bis(guanidine) ligands. These ligands are instrumental in tuning the dioxygen reactivity of copper(I) species, enabling specific catalytic processes.
Preparation of Carbene Complexes
This compound serves as a precursor for generating diaminocarbene- and Fischer-carbene complexes of palladium and nickel. This is achieved through oxidative insertion reactions, forming new organometallic compounds for catalysis.
Lanthanide Complexation Studies
It is employed in the synthesis of neodymium and europium complexes featuring amides and cyclic aminoxides. Furthermore, bis(pentamethylene)urea complexes of lanthanide nitrates and europium complexes for luminescence studies also utilise this reagent.
Formation of Tetra(amino)methanes
1,1′-Carbonyldipiperidine is a reactant in the synthesis of tetra(amino)methanes, a class of organic compounds with potential applications in materials science and as synthetic intermediates.
| Molecular weight | 196.29 |
|---|---|
| Empirical formula | C11H20N2O |
| Assay | 97% |
| Boiling point | 296-298 °C(lit.) |
| Application | Reactant for synthesis of:• Bis(guanidine) ligands for tuning of copper(I) dioxygen reactivity1• Diaminocarbene- and Fischer-carbene complexes of palladium and nickel by oxidative insertion2• Neodymium and europium complexes with amides and cyclic aminoxides3• Bis(pentamethylene)urea complexes of lanthanide nitrates4• Europium complexes for luminescence studies5• Tetra(amino)methanes6 |
| Melting point | 44-47 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 113 °C / 235.4 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1′-Carbonyldipiperidine primarily used for?
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1,1′-Carbonyldipiperidine is primarily used as a reactant for the synthesis of specialised ligands, metal complexes (including lanthanides), and carbene complexes for various chemical research applications.
What is the CAS number and molecular formula for 1,1′-Carbonyldipiperidine?
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The CAS number for 1,1′-Carbonyldipiperidine is 5395-04-0, and its empirical formula (Hill notation) is C11H20N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,1′-Carbonyldipiperidine with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations when handling 1,1′-Carbonyldipiperidine?
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1,1′-Carbonyldipiperidine is classified as harmful if swallowed (H302) and causes serious eye irritation (H319). Always handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is 1,1′-Carbonyldipiperidine packed and shipped?
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Tech Serve Solutions exports chemicals globally, ensuring appropriate packaging and documentation for safe and compliant international shipment. Specific packing details are available upon request.
How can I request a sample or quote for 1,1′-Carbonyldipiperidine?
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To request a sample or a quotation for 1,1′-Carbonyldipiperidine, please contact our sales department via the website or direct email, providing your contact details and required quantity.
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