Palmitic anhydride
Palmitic anhydride (CAS: 623-65-4), with the molecular formula [CH3(CH2)14CO]2O and a molecular weight of 494.83 g/mol, is a carboxylic acid anhydride derived from palmitic acid. It serves as a valuable reagent in organic synthesis, particularly for acylation reactions. Its primary applications include the preparation of esters and amides, and it is also employed as a building block in the synthesis of more complex organic molecules within the biochemical and lipid research fields.
- IUPAC
- Hexadecanoic anhydride
- Synonyms
- Hexadecanoic anhydride
![Palmitic anhydride ([CH3(CH2)14CO]2O) — chemical structure, CAS 623-65-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F623-65-4.png&w=3840&q=75)
Acylating Agent in Organic Synthesis
Palmitic anhydride is utilized as an acylating agent to introduce the palmitoyl group into various organic molecules. This is commonly achieved through reactions with alcohols and amines to form corresponding esters and amides, respectively.
Synthesis of Lipids and Derivatives
As a derivative of palmitic acid, it plays a role in the synthesis and modification of lipids and related compounds. This includes the preparation of complex fatty acid esters and conjugates used in biochemical research.
Building Block for Complex Molecules
Its structure makes it a useful building block in the multi-step synthesis of larger, more complex organic structures. Researchers employ it in the development of novel compounds for diverse chemical and biological investigations.
| Molecular weight | 494.83 |
|---|---|
| Linear formula | [CH3(CH2)14CO]2O |
| Assay | ≥90%~99% fatty acid basis |
| Storage temperature | 2-8°C |
| Melting point | 61-64 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Type | Grade II |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Palmitic anhydride used for?
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Palmitic anhydride is primarily used as an acylating agent in organic synthesis for preparing esters and amides, and as a building block in the synthesis of lipids and other complex organic molecules.
What are the CAS number and molecular formula for Palmitic anhydride?
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The CAS number for Palmitic anhydride is 623-65-4, and its molecular formula is [CH3(CH2)14CO]2O.
What grade and purity does Tech Serve Solutions supply for Palmitic anhydride?
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Tech Serve Solutions supplies Palmitic anhydride in Grade II with an assay of ≥90%, typically around ~99% on a fatty acid basis. We do not represent this product as USP, BP, or EP grade.
How should Palmitic anhydride be handled safely?
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Palmitic anhydride is classified as corrosive, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves, must be worn. Handling should occur in a well-ventilated area, and spill procedures should be readily available.
Is Palmitic anhydride a controlled substance?
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Based on the provided data, Palmitic anhydride is not listed as a controlled substance.
How is Palmitic anhydride typically packed and shipped?
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Palmitic anhydride is typically stored at 2-8°C. Shipping is carried out according to UN 3261 regulations for corrosive solids, acidic, organic, n.o.s. (Palmitic anhydride).
How can I request a quote or sample for Palmitic anhydride?
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To request a quote or sample for Palmitic anhydride, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
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