Pam3-Cys-OH

CAS 87420-41-5C54H103NO7SChemical Synthesis

Pam3-Cys-OH (CAS: 87420-41-5) is a lipidated cysteine derivative with the molecular formula C54H103NO7S and a molecular weight of 910.46 g/mol. This compound serves as a valuable tool in biochemical research, particularly in studies related to cell signalling, immunology, and the development of novel therapeutic agents. Its structure facilitates interaction with biological membranes, making it useful for investigating lipid-protein interactions and cellular responses.

IUPAC: N-α-Palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-L-cysteine,Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-OH
Synonyms: N-α-Palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-L-cysteine,Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-OH

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Pam3-Cys-OH (C54H103NO7S) — chemical structure, CAS 87420-41-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesCell BiologyChemical BiologyChemical SynthesisCysteine/CystineOther PeptidesPeptide ChemistryPeptides and Proteins

01 /Applications

Immunological Research

Pam3-Cys-OH is frequently used as a synthetic toll-like receptor 2 (TLR2) agonist. It mimics bacterial lipopeptides, enabling researchers to study innate immune responses and the activation pathways of immune cells.

Cell Signalling Studies

This compound is instrumental in exploring signalling cascades triggered by TLR2 activation. It helps researchers elucidate downstream effects on cytokine production and cellular activation in various cell types.

Drug Discovery and Development

As a potent immune modulator, Pam3-Cys-OH can be employed in preclinical research for the development of adjuvants or immunotherapies. Its use aids in understanding how to effectively stimulate or modulate the immune system for therapeutic benefit.

Chemical Biology Investigations

The lipidated nature of Pam3-Cys-OH makes it suitable for investigating interactions with cellular membranes and lipid-binding proteins. This aids in understanding molecular mechanisms at the cellular interface.

02 /Properties

Molecular weight	910.46
Empirical formula	C54H103NO7S
Assay	≥98.0% (TLC)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

87420-41-5

MDL number

MFCD00153468

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Pam3-Cys-OH used for?

Pam3-Cys-OH is primarily used in immunological research as a Toll-like receptor 2 (TLR2) agonist to study innate immune responses. It is also valuable in cell signalling investigations, drug discovery, and chemical biology for exploring membrane interactions.

What are the CAS number and formula for Pam3-Cys-OH?

The CAS number for Pam3-Cys-OH is 87420-41-5, and its empirical formula is C54H103NO7S.

What grade and purity does Tech Serve Solutions supply for Pam3-Cys-OH?

Tech Serve Solutions supplies Pam3-Cys-OH with a purity of ≥98.0% (TLC). This is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeial standard.

What are the safety and handling requirements for Pam3-Cys-OH?

Pam3-Cys-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It carries a WGK Germany rating of 3, indicating a high hazard.