Palmitoyl chloride
Palmitoyl chloride (CAS: 112-67-4), with the linear formula CH3(CH2)14COCl and a molecular weight of 274.87 g/mol, is an acid halide. This compound serves as a crucial building block in organic synthesis, particularly for introducing the palmitoyl group into other molecules. It is widely employed in chemical synthesis and finds applications in areas such as cell biology and post-translational modification research.
- IUPAC
- Hexadecanoyl chloride
- Synonyms
- Hexadecanoyl chloride
Organic Synthesis Intermediate
Palmitoyl chloride acts as an acylating agent, facilitating the introduction of the C16 fatty acyl chain into various organic molecules. This is essential for synthesizing complex organic compounds and modifying existing ones.
Biochemical Research
It is utilised in studies involving cell signalling and neuroscience, particularly for investigating post-translational modifications like protein acylation. This helps researchers understand cellular processes and disease mechanisms.
Reagent for Acylation
As a reactive acid halide, it readily reacts with nucleophiles such as alcohols and amines. This property makes it a valuable reagent for the synthesis of esters and amides, which are important in various chemical industries.
| Molecular weight | 274.87 |
|---|---|
| Linear formula | CH3(CH2)14COCl |
| Assay | ≥97.0% (GC) |
| Boiling point | 88-90 °C/0.2 mmHg(lit.) |
| Density | 0.907 g/mL at 20 °C0.906 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.452(lit.)n20/D 1.452 |
| Melting point | 11-13 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 160 °C / 320 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Palmitoyl chloride used for?
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Palmitoyl chloride (CAS: 112-67-4) is primarily used as an intermediate in organic synthesis for introducing the palmitoyl group into molecules, and in biochemical research related to cell biology and post-translational modifications.
What is the CAS number and formula for Palmitoyl chloride?
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The CAS number for Palmitoyl chloride is 112-67-4 and its linear formula is CH3(CH2)14COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Palmitoyl chloride with a purity of ≥97.0% (GC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for Palmitoyl chloride?
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Palmitoyl chloride is a corrosive substance that reacts violently with water, causing severe skin burns and eye damage. Handling requires appropriate personal protective equipment, including faceshields, gloves, goggles, and suitable respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for detailed information.
How is Palmitoyl chloride packed and exported by Tech Serve Solutions?
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Palmitoyl chloride is packed according to international shipping regulations for hazardous materials (UN 3265, Class 8, PG II) and exported globally by Tech Serve Solutions.
How can I request a quote or sample of Palmitoyl chloride?
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To request a quote or sample of Palmitoyl chloride, please contact our sales team via the website or by phone, providing your specific requirements.
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