2,4-Difluorobenzyl bromide
2,4-Difluorobenzyl bromide (CAS: 23915-07-3) is an organic compound with the molecular formula C7H5BrF2 and a molar mass of 207.02 g/mol. This fluorinated aromatic building block is utilised in chemical synthesis. Its applications include the preparation of novel heterocyclic compounds and pharmaceutical intermediates, contributing to the development of new therapeutic agents. Tech Serve Solutions provides this chemical with a minimum assay of 98%.
- IUPAC
- α-Bromo-2,4-difluorotoluene
- Synonyms
- F2C6H3CH2Brα-Bromo-2,4-difluorotoluene
Synthesis of Triazolium Derivatives
2,4-Difluorobenzyl bromide serves as a key intermediate in the synthesis of novel 1,2,4-triazolium derivatives. These compounds may find applications in medicinal chemistry research.
Development of Receptor Antagonists
This compound is employed in the preparation of 1,5-biaryl pyrrole derivatives which act as EP1 receptor antagonists. Such research contributes to the discovery of new pharmacological agents.
Fluorinated Organic Synthesis
As a versatile fluorinated building block, 2,4-Difluorobenzyl bromide facilitates the introduction of the 2,4-difluorobenzyl moiety into various organic structures, enabling access to a range of specialised chemical entities.
| Molecular weight | 207.02 |
|---|---|
| Linear formula | F2C6H3CH2Br |
| Assay | 98% |
| Density | 1.613 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.525(lit.) |
| Application | 2,4-Difluorobenzyl bromide has been used in the preparation of:• novel 1,2,4-triazolium derivatives1• 1,5-biaryl pyrrole EP1 receptor antagonists2 |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 40 °C / 104 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34-42/43 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluorobenzyl bromide used for?
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2,4-Difluorobenzyl bromide is used in chemical synthesis, particularly for preparing novel 1,2,4-triazolium derivatives and 1,5-biaryl pyrrole EP1 receptor antagonists, among other fluorinated organic compounds.
What are the CAS number and formula for 2,4-Difluorobenzyl bromide?
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The CAS number for 2,4-Difluorobenzyl bromide is 23915-07-3, and its linear formula is F2C6H3CH2Br.
What grade and purity does Tech Serve Solutions supply for 2,4-Difluorobenzyl bromide?
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Tech Serve Solutions supplies 2,4-Difluorobenzyl bromide with a minimum assay of 98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product data.
How should 2,4-Difluorobenzyl bromide be handled safely?
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2,4-Difluorobenzyl bromide is a dangerous substance. It is flammable (Flash Point 40°C), causes severe skin burns and eye damage, and may cause an allergic skin reaction and respiratory irritation. Handle with extreme care using appropriate personal protective equipment, including gloves, goggles, face shield, and a suitable respirator. Ensure adequate ventilation and avoid ignition sources.
How is 2,4-Difluorobenzyl bromide packed, shipped, and exported?
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2,4-Difluorobenzyl bromide is packed and shipped according to international regulations for hazardous materials (UN 2920, Class 3(8), PGII). Tech Serve Solutions has extensive experience in global export of chemicals.
How can I request a sample or quote for 2,4-Difluorobenzyl bromide?
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To request a sample or a quote for 2,4-Difluorobenzyl bromide, please contact our sales team through the website or by phone. We aim to respond promptly to all inquiries.
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