2,4-Difluorobenzonitrile
2,4-Difluorobenzonitrile (CAS: 3939-09-1; Formula: F2C6H3CN; MW: 139.10) is a valuable organic building block and a fluorinated aromatic compound. Utilised in chemical synthesis, it serves as a key intermediate in the creation of more complex molecules, particularly within the pharmaceutical and agrochemical sectors. Its distinct difluoro-substitution pattern makes it a versatile reagent for introducing fluorinated phenyl rings into various organic structures.
- Synonyms
- F2C6H3CN
Synthesis of Fluoro-Substituted Amines
2,4-Difluorobenzonitrile is employed in the synthesis of specialized amine compounds. For instance, it is a precursor in the preparation of 2-methylsulfonyl-4-fluorobenzylamine, a molecule with potential applications in medicinal chemistry.
Intermediate for Heterocyclic Compounds
This compound acts as a building block for constructing fluorinated heterocyclic systems. It has been utilised in the synthesis of fluoro-3-amino-1,2-benzisoxazoles, which are important scaffolds in drug discovery.
Fluorinated Aromatic Synthesis
As a readily available source of a 2,4-difluorophenyl moiety, 2,4-Difluorobenzonitrile is a useful reagent for organic chemists developing novel fluorinated compounds. Its nitrile group allows for further chemical transformations.
| Molecular weight | 139.10 |
|---|---|
| Linear formula | F2C6H3CN |
| Assay | 97% |
| Application | 2,4-Difluorobenzonitrile has been used in the synthesis of:• 2-methylsulfonyl-4-fluorobenzylamine1• fluoro-3-amino-1,2-benzisoxazoles2 |
| Melting point | 47-49 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluorobenzonitrile used for?
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2,4-Difluorobenzonitrile is primarily used as a building block in organic synthesis, particularly for preparing fluorinated aromatic compounds and heterocyclic structures. It has been used in the synthesis of compounds like 2-methylsulfonyl-4-fluorobenzylamine and fluoro-3-amino-1,2-benzisoxazoles.
What are the CAS number and formula for 2,4-Difluorobenzonitrile?
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The CAS number for 2,4-Difluorobenzonitrile is 3939-09-1, and its linear formula is F2C6H3CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Difluorobenzonitrile with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,4-Difluorobenzonitrile be handled safely?
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2,4-Difluorobenzonitrile is harmful if swallowed, in contact with skin, and if inhaled. It also causes skin irritation, serious eye irritation, and respiratory irritation. Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
Is 2,4-Difluorobenzonitrile available for export globally?
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Yes, Tech Serve Solutions specialises in supplying and exporting fine chemicals like 2,4-Difluorobenzonitrile to customers worldwide.
How can I request a quote or sample for 2,4-Difluorobenzonitrile?
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To request a quote or a sample of 2,4-Difluorobenzonitrile, please contact our sales team through the website or by phone.
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