Oxaliplatin
Oxaliplatin (CAS: 61825-94-3; Formula: C8H14N2O4Pt) is a platinum-based antineoplastic agent used in cancer chemotherapy. It functions by cross-linking DNA, inhibiting DNA replication and transcription, which ultimately leads to cancer cell death. This compound is a key component in combination therapies for treating advanced colorectal cancer and other solid tumours. Its molecular weight is 397.29 g/mol.
- IUPAC
- [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N′)[ethanedioata(2--)-O,O’]platinum
Antineoplastic Agent
Oxaliplatin is a platinum-based chemotherapy drug primarily utilised in the treatment of advanced colorectal cancer. It acts by forming DNA adducts, disrupting DNA replication and transcription in rapidly dividing cancer cells.
Cancer Research
As a significant chemotherapeutic agent, Oxaliplatin is frequently employed in research settings to study mechanisms of cancer cell death and drug resistance. It serves as a valuable tool in developing novel therapeutic strategies.
DNA Crosslinking Agent
The mechanism of action involves forming intra-strand and inter-strand cross-links within the DNA structure. This DNA damage triggers apoptosis and cell cycle arrest, contributing to its cytotoxic effects against tumour cells.
| Molecular weight | 397.29 |
|---|---|
| Empirical formula | C8H14N2O4Pt |
| Form | solid |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-40-42/43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Oxaliplatin used for?
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Oxaliplatin is a platinum-based antineoplastic agent primarily used in combination chemotherapy for advanced colorectal cancer and other solid tumours.
What is the CAS number and formula for Oxaliplatin?
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The CAS number for Oxaliplatin is 61825-94-3, and its empirical formula (Hill Notation) is C8H14N2O4Pt.
What grade and purity does Tech Serve Solutions supply for Oxaliplatin?
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Tech Serve Solutions supplies Oxaliplatin for research purposes. The purity and grade are not specified as USP, BP, or EP unless explicitly stated in the product documentation. Customers should consult the Certificate of Analysis for specific lot details.
How should Oxaliplatin be handled safely?
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Oxaliplatin is a hazardous substance requiring careful handling. It is classified with Warning signal word and hazard statements H315 (Causes skin irritation), H317 (May cause an allergic skin reaction), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation), and H351 (Suspected of causing cancer). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be used. Store at 2-8°C.
How is Oxaliplatin typically packed and shipped?
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Oxaliplatin is typically supplied as a solid and requires storage at 2-8°C. TSS exports fine chemicals globally, adhering to all necessary shipping regulations.
How can I request a sample or quote for Oxaliplatin?
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To request a sample or quote for Oxaliplatin, please contact our sales department through the website or by phone, providing your specific requirements.
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