1-(2-Methylphenyl)piperidin-4-one
1-(2-Methylphenyl)piperidin-4-one (CAS 218610-72-1) is an N-aryl piperidin-4-one with the molecular formula C12H15NO and a molar mass of 189.25 g/mol. This heterocyclic building block pairs a reactive 4-oxopiperidine ring with an ortho-tolyl (2-methylphenyl) substituent on nitrogen. The ketone and the piperidine scaffold make it a versatile intermediate for chemical synthesis and structure-activity studies. Tech Serve Solutions supplies it as a research-grade building block to laboratories worldwide.
- Synonyms
- 1-(2-Methylphenyl)piperidin-4-one1-(2-methylphenyl)-4-piperidinone1-(o-tolyl)piperidin-4-one1-(2-tolyl)-4-piperidoneN-(2-methylphenyl)-4-piperidone4-Piperidinone, 1-(2-methylphenyl)-CAS 218610-72-1
Heterocyclic building block
Serves as an N-arylated piperidin-4-one scaffold in multi-step organic synthesis. The pre-installed 2-methylphenyl group on nitrogen lets chemists elaborate the ring without a separate N-arylation step.
Ketone-directed functionalisation
The 4-oxo group is a reactive handle for reductive amination, condensation, Grignard addition, enolate chemistry and reduction to the corresponding piperidin-4-ol, enabling rapid access to substituted piperidine derivatives.
Medicinal-chemistry intermediate
Substituted piperidin-4-ones are common cores in discovery chemistry. This compound is used as a starting material for analogue libraries and structure-activity relationship work at research scale.
Reference and research material
Supplied for laboratory research, method development and analytical work where a defined N-aryl piperidinone is required.
| Molecular weight | 189.25 |
|---|---|
| Empirical formula | C12H15NO |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Methylphenyl)piperidin-4-one used for?
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It is used mainly as a heterocyclic building block and synthetic intermediate. The reactive 4-ketone and N-(2-methylphenyl) piperidine ring make it a convenient scaffold for reductive amination, condensation and other transformations in research-scale organic and medicinal chemistry.
What is the CAS number and molecular formula of 1-(2-Methylphenyl)piperidin-4-one?
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The CAS number is 218610-72-1. The molecular formula is C12H15NO (Hill notation), corresponding to a molecular weight of 189.25 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(2-Methylphenyl)piperidin-4-one as a technical/research-grade building block for laboratory and synthetic use. We do not represent it as USP, BP or EP pharmacopoeia grade. A current Certificate of Analysis with the exact assay and lot specifications is provided with each consignment on request.
What are the safety and handling precautions?
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Handle as a research chemical for which a full hazard profile may not be established. Use only in a properly ventilated laboratory by trained personnel, wear suitable gloves, eye protection and a lab coat, avoid dust, skin and eye contact, and keep away from incompatible materials. Always follow the current Safety Data Sheet, which we supply with the product.
How is 1-(2-Methylphenyl)piperidin-4-one packed, shipped and exported?
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It is packed in tightly closed, appropriately labelled containers sized to the order, from gram research quantities to larger volumes. As a global exporter since 1998, Tech Serve Solutions arranges compliant international documentation and shipping, with packaging and transport handled per the applicable regulations for the destination.
How do I request a sample or quote?
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Send us the quantity, required packaging and your destination through the enquiry or quote form, and our team will respond with availability, lead time and documentation, including the Certificate of Analysis and Safety Data Sheet.
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