2,3-Difluorobenzylamine
2,3-Difluorobenzylamine (CAS 72235-51-9) is a fluorinated aromatic amine with the molecular formula F₂C₆H₃CH₂NH₂ and a molecular weight of 143.13 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where precise fluorination is required. Its chemical structure makes it useful for introducing the 2,3-difluorobenzyl moiety into more complex molecules.
- Synonyms
- F2C6H3CH2NH2
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs), where the difluorinated phenyl ring can influence pharmacokinetic properties and receptor binding. Its amine functionality allows for various coupling and derivatisation reactions.
Agrochemical Development
Incorporated into the molecular design of novel pesticides and herbicides. Fluorine atoms can enhance metabolic stability and efficacy of agrochemical compounds.
Material Science Research
Potential use in the synthesis of specialised polymers or functional materials where the electronic properties of the fluorinated aromatic system are exploited.
Organic Synthesis Building Block
A versatile reagent for introducing the 2,3-difluorobenzyl group in a wide range of organic transformations. Its reactivity is characteristic of primary benzylamines.
| Molecular weight | 143.13 |
|---|---|
| Linear formula | F2C6H3CH2NH2 |
| Assay | 97% |
| Boiling point | 65 °C/4 mmHg(lit.) |
| Density | 1.223 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.495(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 77 °C / 170.6 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluorobenzylamine used for?
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2,3-Difluorobenzylamine (CAS 72235-51-9) is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also employed in material science research.
What is the CAS number and chemical formula for 2,3-Difluorobenzylamine?
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The CAS number is 72235-51-9, and the linear chemical formula is F₂C₆H₃CH₂NH₂.
What grade and purity does Tech Serve Solutions supply for 2,3-Difluorobenzylamine?
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Tech Serve Solutions supplies 2,3-Difluorobenzylamine with an assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,3-Difluorobenzylamine be handled safely?
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2,3-Difluorobenzylamine is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, gloves, goggles, and suitable respiratory protection, is essential. Handle in a well-ventilated area and follow all safety precautions outlined in the Safety Data Sheet.
Is 2,3-Difluorobenzylamine exported or shipped internationally by TSS?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,3-Difluorobenzylamine. We ship products worldwide.
How can I request a quote or sample for 2,3-Difluorobenzylamine?
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To request a quote or sample, please contact our sales department via the website or by phone. Specify the product name and CAS number (72235-51-9) in your request.
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