2,3-Difluoromandelic acid
2,3-Difluoromandelic acid (CAS: 207974-19-4), with the molecular formula C8H6F2O3, is a valuable fluorinated organic building block. This carboxylic acid derivative offers unique chemical properties due to its difluorinated phenyl ring and chiral center. It serves as a key intermediate in organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where fluorine substitution can impart desirable characteristics such as enhanced metabolic stability and binding affinity. Its precise structure makes it ideal for targeted chemical modifications.
- IUPAC
- 2′,3′-Difluoro-2-hydroxyphenylacetic acid,2,3-Difluoro-α-hydroxyphenylacetic acid
- Synonyms
- C8H6F2O32′,3′-Difluoro-2-hydroxyphenylacetic acid2,3-Difluoro-α-hydroxyphenylacetic acid

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the difluoromandelic acid moiety can introduce specific physicochemical properties or act as a chiral scaffold for drug development.
Agrochemical Development
Serves as a building block for novel pesticides, herbicides, and fungicides, leveraging fluorine's ability to influence biological activity and environmental persistence.
Material Science Research
Investigated for potential applications in advanced materials, such as polymers or liquid crystals, where its unique electronic and structural features can be exploited.
Organic Synthesis Reagent
A versatile starting material for creating complex fluorinated organic molecules through various chemical transformations.
| Molecular weight | 188.13 |
|---|---|
| Empirical formula | C8H6F2O3 |
| Assay | 97% |
| Melting point | 109-113 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluoromandelic acid used for?
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2,3-Difluoromandelic acid is primarily used as a building block in organic synthesis, particularly for pharmaceuticals and agrochemicals, and in material science research.
What is the CAS number and formula for 2,3-Difluoromandelic acid?
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The CAS number is 207974-19-4 and the empirical formula is C8H6F2O3.
What grade and purity does Tech Serve Solutions supply for 2,3-Difluoromandelic acid?
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Tech Serve Solutions supplies 2,3-Difluoromandelic acid with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling considerations for 2,3-Difluoromandelic acid?
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2,3-Difluoromandelic acid has a WGK Germany rating of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area.
How is 2,3-Difluoromandelic acid packed, shipped, and exported by TSS?
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Tech Serve Solutions packs, ships, and exports chemicals globally, adhering to all relevant transportation and regulatory requirements for hazardous materials.
How can I request a quote or sample of 2,3-Difluoromandelic acid?
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To request a quote or sample of 2,3-Difluoromandelic acid, please contact our sales department through the website or by phone.
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