2,3-Difluorophenylboronic acid

CAS 121219-16-7F2C6H3B(OH)2Chemical Synthesis

2,3-Difluorophenylboronic acid (CAS: 121219-16-7) is an organoboron compound with the molecular formula F2C6H3B(OH)2 and a molecular weight of 157.91 g/mol. This aryl boronic acid serves as a key reactant in Suzuki-Miyaura cross-coupling reactions. It is instrumental in the preparation of complex organic molecules, particularly those with biological and pharmacological relevance, making it a valuable reagent in synthetic chemistry.

IUPAC: 2,3-Difluorobenzeneboronic acid
Synonyms: F2C6H3B(OH)22,3-Difluorobenzeneboronic acid

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2,3-Difluorophenylboronic acid (F2C6H3B(OH)2) — chemical structure, CAS 121219-16-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Aryl Boronic AcidsBoronic AcidsChemical Synthesis

01 /Applications

Suzuki-Miyaura Cross-Coupling

Utilised as a coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds for constructing complex molecular architectures.

Pharmaceutical Intermediate Synthesis

Serves as a crucial building block in the synthesis of biologically active molecules and potential drug candidates, facilitating the introduction of the difluorophenyl moiety.

Organic Synthesis Reagent

A versatile reagent employed in general organic synthesis for the preparation of advanced intermediates and fine chemicals.

02 /Properties

Molecular weight	157.91
Linear formula	F2C6H3B(OH)2
Application	Reactant for:• Suzuki-Miyaura cross-coupling reactions1• Preparation of biologically and pharmacologically active molecules2,3
Melting point	95 °C (dec.)(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

121219-16-7

MDL number

MFCD01863170

PubChem substance

24873735

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,3-Difluorophenylboronic acid primarily used for?

2,3-Difluorophenylboronic acid is primarily used as a reactant in Suzuki-Miyaura cross-coupling reactions and for the preparation of biologically and pharmacologically active molecules.

What is the CAS number and formula for 2,3-Difluorophenylboronic acid?

The CAS number is 121219-16-7, and the linear formula is F2C6H3B(OH)2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are not detailed as USP, BP, or EP. Please contact us for detailed specifications.

What are the safety considerations when handling 2,3-Difluorophenylboronic acid?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating it is hazardous.

How is 2,3-Difluorophenylboronic acid typically packed and shipped?

Tech Serve Solutions specialises in the global supply and export of fine chemicals. Products are carefully packed to ensure safe transit and compliance with international shipping regulations.