2,3-Difluoropyridine-4-carboxylic acid
2,3-Difluoropyridine-4-carboxylic acid (CAS: 851386-31-7) is a fluorinated heterocyclic compound with the molecular formula C6H3F2NO2 and a molecular weight of 159.09 g/mol. This building block is valuable in organic synthesis, particularly for introducing difluoropyridine moieties into more complex molecules. It finds application in the development of novel pharmaceuticals and agrochemicals due to the unique electronic properties conferred by the fluorine atoms.
- IUPAC
- 2,3-Difluoroisonicotinic acid
- Synonyms
- C6H3F2NO22,3-Difluoroisonicotinic acid

Pharmaceutical Intermediates
Used in the synthesis of active pharmaceutical ingredients (APIs), leveraging the pyridine ring and fluorine substituents to modulate drug properties such as bioavailability and metabolic stability.
Agrochemical Development
Serves as a key intermediate in the creation of novel pesticides and herbicides, where the fluorinated pyridine structure can enhance efficacy and environmental profile.
Materials Science Research
Explored for incorporation into functional materials, where its unique electronic and structural characteristics can be exploited for advanced applications.
Organic Synthesis Building Block
A versatile reagent for introducing the 2,3-difluoropyridin-4-yl group in diverse synthetic pathways, enabling the construction of complex organic molecules.
| Molecular weight | 159.09 |
|---|---|
| Empirical formula | C6H3F2NO2 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 163-168 °C |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluoropyridine-4-carboxylic acid used for?
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2,3-Difluoropyridine-4-carboxylic acid is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals, and in materials science research.
What is the CAS number and molecular formula?
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The CAS number for 2,3-Difluoropyridine-4-carboxylic acid is 851386-31-7 and its molecular formula is C6H3F2NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Difluoropyridine-4-carboxylic acid with an assay of 97%. We do not represent this product as USP, BP, EP or pharmaceutical grade.
What are the safety and handling precautions for this chemical?
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This compound is classified with a GHS07 symbol and a Warning signal word. It carries the hazard statement H302 (Harmful if swallowed). Handle with appropriate personal protective equipment and consult the Safety Data Sheet (SDS) for detailed handling and storage information. Recommended storage is between 2-8°C.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging and compliance for international shipment.
How can I request a sample or quote?
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To request a sample or a quote for 2,3-Difluoropyridine-4-carboxylic acid, please contact our sales team through the website or via direct inquiry.
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