2,3-Difluoropyridine
2,3-Difluoropyridine (CAS: 1513-66-2) is a fluorinated heterocyclic building block with the molecular formula C5H3F2N and a molecular weight of 115.08 g/mol. It serves as a valuable intermediate in organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. Its unique difluorinated pyridine structure enables diverse chemical transformations, making it a key component in the creation of complex molecules.
- Synonyms
- C5H3F2N

Pharmaceutical Intermediate
2,3-Difluoropyridine is utilised in the synthesis of active pharmaceutical ingredients (APIs). The incorporation of fluorine atoms can modulate properties such as metabolic stability, lipophilicity, and binding affinity, leading to improved drug candidates.
Agrochemical Synthesis
This compound is employed in the development of new pesticides, herbicides, and fungicides. Fluorinated heterocycles often exhibit enhanced biological activity and favourable environmental profiles.
Materials Science
Its unique electronic and structural properties make 2,3-Difluoropyridine a potential building block for advanced materials, including polymers and organic electronic components.
Research and Development
As a versatile fluorinated building block, it is frequently used in academic and industrial research labs for exploring new synthetic routes and discovering novel compounds.
| Molecular weight | 115.08 |
|---|---|
| Empirical formula | C5H3F2N |
| Assay | 95% |
| Density | 1.265 g/mL at 25 °C |
| Refractive index | n20/D 1.427 |




Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H318Causes serious eye damage
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | 26 °C / 78.8 °F |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 10-22-41-50 |
| Safety statements (S) | 16-25-26-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluoropyridine used for?
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2,3-Difluoropyridine is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and advanced materials. It is also widely employed in chemical research and development.
What are the CAS number and molecular formula for 2,3-Difluoropyridine?
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The CAS number for 2,3-Difluoropyridine is 1513-66-2, and its molecular formula is C5H3F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Difluoropyridine with a minimum assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 2,3-Difluoropyridine be handled safely?
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2,3-Difluoropyridine is a flammable liquid and vapour (H226) and is harmful if swallowed (H302). It causes serious eye damage (H318) and is very toxic to aquatic life with long-lasting effects (H400). Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet for detailed handling and storage information.
How is 2,3-Difluoropyridine packed and shipped?
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2,3-Difluoropyridine is packed and shipped according to international regulations for hazardous materials, including UN 1993 classification. We are experienced in exporting chemicals globally.
How can I request a sample or quote for 2,3-Difluoropyridine?
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To request a sample or a quote, please contact our sales team through the website or by phone. Please specify the quantity required and your delivery location.
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