Norclomipramine hydrochloride
Norclomipramine hydrochloride (CAS: 303-48-0) is a chemical compound with the molecular formula C18H21ClN2 · HCl and a molecular weight of 337.29 g/mol. It is primarily utilized as a building block in chemical synthesis, particularly within heterocyclic chemistry. This compound is a derivative of clomipramine and serves as a valuable intermediate for researchers and chemists developing novel organic molecules and pharmaceuticals. Its precise structure makes it suitable for various synthetic routes.
- IUPAC
- N-Desmethylclomipramine
- Synonyms
- N-Desmethylclomipramine

Chemical Synthesis Intermediate
Norclomipramine hydrochloride serves as a key intermediate in the synthesis of complex organic molecules. Its specific chemical structure is valuable for introducing the N-desmethylclomipramine moiety into larger compounds during multi-step syntheses.
Heterocyclic Chemistry Building Block
As a heterocyclic building block, this compound is employed in the construction of diverse nitrogen-containing heterocyclic systems. These systems are fundamental in medicinal chemistry and materials science research.
Pharmaceutical Research
Researchers in the pharmaceutical industry may use Norclomipramine hydrochloride as a starting material or intermediate in the development of new drug candidates. Its structural relation to known pharmacologically active compounds makes it of interest.
| Molecular weight | 337.29 |
|---|---|
| Empirical formula | C18H21ClN2 · HCl |
| Assay | ~99% (TLC) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Norclomipramine hydrochloride used for?
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Norclomipramine hydrochloride is primarily used as a building block and intermediate in chemical synthesis, particularly in heterocyclic chemistry and pharmaceutical research.
What is the CAS number and molecular formula for Norclomipramine hydrochloride?
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The CAS number for Norclomipramine hydrochloride is 303-48-0, and its molecular formula is C18H21ClN2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Norclomipramine hydrochloride with an assay of approximately 99% (determined by TLC). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, or EP grade.
How should Norclomipramine hydrochloride be handled?
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Norclomipramine hydrochloride is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, must be used. Handle in a well-ventilated area.
Is Norclomipramine hydrochloride a controlled substance?
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Based on the provided data, Norclomipramine hydrochloride is not listed as a controlled substance. However, users should always verify local regulations.
How is Norclomipramine hydrochloride shipped and exported?
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Tech Serve Solutions, as a global supplier and exporter, ships chemicals like Norclomipramine hydrochloride in compliance with international shipping regulations for hazardous materials. Contact us for specific export inquiries.
How can I request a sample or quote for Norclomipramine hydrochloride?
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To request a sample or a quote for Norclomipramine hydrochloride, please visit the Tech Serve Solutions website or contact our sales department directly through the provided contact information.
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