2,3-Difluorophenol
2,3-Difluorophenol (CAS: 6418-38-8), with the linear formula F₂C₆H₃OH and a molecular weight of 130.09 g/mol, is a key organic building block. This fluorinated phenol serves as a crucial intermediate in chemical synthesis, particularly in the development of advanced materials. Its unique structure makes it valuable for creating specialised polymers and compounds, enabling applications in materials science and potentially in detection systems.
- Synonyms
- F2C6H3OH2,3-Difluorbenzenol

Synthesis of Organophosphate-Sensitive Materials
2,3-Difluorophenol is utilized in the synthesis of specialised polymers, such as poly{methyl[3-(2-hydroxy-3,4-difluoro)phenyl]propyl siloxane} (PMDFPS). These materials exhibit sensitivity to toxic organophosphates, finding potential applications in detection technologies.
Fluorinated Building Block in Organic Synthesis
As an organic fluorinated building block, 2,3-Difluorophenol is a valuable precursor in the construction of complex organic molecules. The presence of fluorine atoms can impart unique electronic and steric properties to the final compounds.
Development of Novel Chemical Entities
This compound serves as an intermediate in the broader field of chemical synthesis, contributing to the development of novel chemical entities for research and industrial applications where fluorinated aromatic structures are required.
| Molecular weight | 130.09 |
|---|---|
| Linear formula | F2C6H3OH |
| Assay | 98% |
| Boiling point | 54 °C/25 mmHg(lit.) |
| Application | 2,3-Difluorophenol was used in the synthesis of material-poly{methyl[3-(2-hydroxy-3,4-difluoro)phenyl]propyl siloxane} (PMDFPS) sensitive to toxic organophosphate1. |
| Melting point | 39-42 °C(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 57 °C / 134.6 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluorophenol used for?
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2,3-Difluorophenol is primarily used as a building block in organic synthesis and for the creation of specialised materials, such as polymers sensitive to organophosphates.
What is the CAS number and formula for 2,3-Difluorophenol?
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The CAS number for 2,3-Difluorophenol is 6418-38-8, and its linear formula is F₂C₆H₃OH.
What grade and purity does Tech Serve Solutions supply for 2,3-Difluorophenol?
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Tech Serve Solutions supplies 2,3-Difluorophenol with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,3-Difluorophenol be handled safely?
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2,3-Difluorophenol is a flammable liquid and vapour (H226), harmful if swallowed (H302), causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eyeshields, gloves, and ensure adequate ventilation. Consult the Safety Data Sheet for detailed guidance.
Is 2,3-Difluorophenol subject to any special regulations?
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Based on the provided data, 2,3-Difluorophenol is classified with hazard codes F (Flammable) and Xn (Harmful). It requires appropriate handling and transport documentation as indicated by UN 1325.
How is 2,3-Difluorophenol packed, shipped, and exported?
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2,3-Difluorophenol is packed and shipped according to international regulations for hazardous materials. Tech Serve Solutions, as an experienced global supplier, ensures compliant export procedures.
How can I request a sample or quote for 2,3-Difluorophenol?
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To request a sample or a quotation for 2,3-Difluorophenol, please contact our sales team via the website or direct inquiry, providing your specific requirements.
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